Does neutrophil-to-lymphocyte ratio predict active ulcerative colitis?

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-3726-5945en_US
dc.authorid0000-0001-8038-0493
dc.contributor.authorPoşul, Emrah
dc.contributor.authorYılmaz, Bülent
dc.contributor.authorAktaş, Gülali
dc.contributor.authorKurt, Mevlüt
dc.date.accessioned2021-06-23T19:42:09Z
dc.date.available2021-06-23T19:42:09Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Inflammatory markers have been studied in ulcerative colitis (UC) for diagnosis, disease activity, and prediction of relapse. Blood neutrophil-to-lymphocyte (N/L) ratio has been used to determine outcomes of some malignancies and coronary artery disease. Blood N/L ratio is a simple sign of clinical inflammation. In this study, we examined N/L ratio in recurrent patients suffering from UC. Methods The aim of the present study was to analyze N/L ratios in serum samples of UC patients in remission and active phases. Patients' age, extend of the disease, disease duration, disease activity, drug, and other medical history were all noted for patients. C-reactive protein, erythrocyte sedimentation rate, and complete blood count were determined for patients. Results Forty-nine UC patients were admitted into the present study. The blood N/L ratios were significantly increased in active phase compared with inactive UC patients (p < 0.05). The cut-off value for N/L ratio for the detection of active UC patients was calculated as >= 2.3 using receiver operating characteristic analysis [sensitivity: 61.2 %, specificity: 66.7 %, AUC: 0.650 (0.540-0.760), p = 0.01]. Conclusions Present study shows that in patients with UC, the blood N/L ratio is associated with active disease. N/L ratio may be used as an activity parameter in UC.en_US
dc.identifier.doi10.1007/s00508-014-0683-5
dc.identifier.endpage265en_US
dc.identifier.issn0043-5325
dc.identifier.issn1613-7671
dc.identifier.issue7-8en_US
dc.identifier.pmid25576331en_US
dc.identifier.scopus2-s2.0-84929325987en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage262en_US
dc.identifier.urihttps://doi.org/10.1007/s00508-014-0683-5
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8371
dc.identifier.volume127en_US
dc.identifier.wosWOS:000354549100005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorPoşul, Emrah
dc.institutionauthorAktaş, Gülali
dc.institutionauthorKurt, Mevlüt
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofWiener Klinische Wochenschriften_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeutrophil-to-lymphocyte Ratioen_US
dc.subjectSeverityen_US
dc.subjectRecurrenceen_US
dc.subjectUlcerative Colitisen_US
dc.titleDoes neutrophil-to-lymphocyte ratio predict active ulcerative colitis?en_US
dc.typeArticleen_US

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