Multicomponent synthesis of novel thiazolo[3,2-a]pyridin-8-yl-phosphonates as a model of plant growth regulator

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dc.authorid0000-0001-6767-2539en_US
dc.authorid0000-0003-4740-1138en_US
dc.authorid0000-0001-6767-2539
dc.contributor.authorAltuğ, Cevher
dc.contributor.authorYakubu Saleh, Lange
dc.contributor.authorCaner, Esra
dc.contributor.authorGüneş, Hanife
dc.contributor.authorSameeullah, Muhammad
dc.date.accessioned2021-06-23T19:52:38Z
dc.date.available2021-06-23T19:52:38Z
dc.date.issued2019
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.description.abstractA series of thiazolo[3,2-a]pyridin-8-yl-phosphonate derivatives have been obtained by the reaction of diethyl (E)-((4-oxothiazolidin-2-ylidene)methyl)phospohonate, malononitrile and two equivalent of various aromatic aldehydes in a multicomponent reaction with good yields. The structures of the new compounds are confirmed by spectroscopic methods (IR, H-1, C-13, P-31 NMR and HRMS). Compound diethyl-(Z)-(5-amino-6-cyano-2-(4-nitrobenzylidene)-7-(4-nitrophenyl)-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridin -8-yl)phosphonate (4k) at 1mM concentration enhanced biomass plant height, number of branches and leaf area of tomato plants of at least two-fold compared to the control plants. In common bean plants, this compound enhanced the chlorophyl content and delayed senescence in comparison to the control plants. Therefore, in future studies, the compound(s) would be further tested to evaluate deeply their mode of action at physiological, biochemical and molecular level to finally enhance crop productivity of various plants.en_US
dc.identifier.doi10.1080/10426507.2018.1513515
dc.identifier.endpage119en_US
dc.identifier.issn1042-6507
dc.identifier.issn1563-5325
dc.identifier.issue1-2en_US
dc.identifier.scopus2-s2.0-85058386580en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage111en_US
dc.identifier.urihttps://doi.org/10.1080/10426507.2018.1513515
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10183
dc.identifier.volume194en_US
dc.identifier.wosWOS:000469421300015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAltuğ, Cevher
dc.institutionauthorSameeullah, Muhammad
dc.institutionauthorYakubu Saleh, Lange
dc.institutionauthorCaner, Esra
dc.institutionauthorGüneş, Hanife
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofPhosphorus Sulfur And Silicon And The Related Elementsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMulti-component Reactionsen_US
dc.subjectKnoevenagel Reactionen_US
dc.subjectAlkylidene Thiazolidin-4-oneen_US
dc.subjectThiazolopyridineen_US
dc.subjectPhosphonateen_US
dc.subjectPlant Growthen_US
dc.subjectChlorophyll Contenten_US
dc.titleMulticomponent synthesis of novel thiazolo[3,2-a]pyridin-8-yl-phosphonates as a model of plant growth regulatoren_US
dc.typeArticleen_US

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