Evaluation of electrocardiographic ventricular depolarization and repolarization variables in type 1 diabetes mellitus

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dc.authorid0000-0003-2399-9585en_US
dc.authorid0000-0002-3893-5376en_US
dc.authorid0000-0003-1784-3584en_US
dc.authorid0000-0003-3817-851X
dc.contributor.authorİnanır, Mehmet
dc.contributor.authorGüneş, Yılmaz
dc.contributor.authorSincer, İsa
dc.contributor.authorErdal, Emrah
dc.date.accessioned2021-06-23T19:54:35Z
dc.date.available2021-06-23T19:54:35Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The risk of cardiovascular events and sudden death increases with type 1 diabetes mellitus (T1DM). Objective: To evaluate electrocardiographic markers of arrhythmias in T1DM patients. Methods: Electrocardiographic parameters reflecting ventricular depolarization and repolarization, namely, QT, QTc, QTd, QTdc, Tp-e, JT, and JTc intervals and Tp-e/QT and Tp-e/QTc ratios, of 46 patients diagnosed with T1DM were retrospectively analyzed and compared with 46 healthy age-, sex-, and body mass-matched controls. Correlations between T1DM duration, hemoglobin A1c (HbA1c), and ventricular repolarization variables were analyzed. P values lower than 0.05 were considered statistically significant. Results: Diabetes duration was 16.6 +/- 7.1 years, and HbA1c was 10.81% +/- 3.27% in the T1DM group. In comparison with the control group, heart rate, QTc, QTd, QTdc, Tp-e and JTc intervals, Tp-e/QT ratio (p < 0.001), and Tp-e/QTc ratio (p = 0.007) were significantly higher in T1DM patients. T1DM duration and HbA1c levels were significantly correlated with QTc, QTd, QTdc, Tp-e, and JTc intervals and Tp-e/QT and Tp-e/QTc ratios. Conclusions: In T1DM patients, potential electrocardiographic repolarization predictors were significantly increased in correlation with disease duration and HbA1c levels. These findings may contribute to the understanding of sudden cardiac death in patients with T1DM.en_US
dc.identifier.doi10.36660/abc.20180343
dc.identifier.endpage279en_US
dc.identifier.issn0066-782X
dc.identifier.issue2en_US
dc.identifier.pmid32215498en_US
dc.identifier.scopus2-s2.0-85081538371en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage275en_US
dc.identifier.urihttps://doi.org/10.36660/abc.20180343
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10588
dc.identifier.volume114en_US
dc.identifier.wosWOS:000521539200016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorİnanır, Mehmet
dc.institutionauthorSincer, İsa
dc.institutionauthorGüneş, Yılmaz
dc.language.isoenen_US
dc.publisherArquivos Brasileiros Cardiologiaen_US
dc.relation.ispartofArquivos Brasileiros De Cardiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetes Complicationsen_US
dc.subjectRisk Factorsen_US
dc.subjectPrevention and Controlen_US
dc.subjectArrhythmias, Cardiacen_US
dc.subjectElectrocardiography/Methodsen_US
dc.titleEvaluation of electrocardiographic ventricular depolarization and repolarization variables in type 1 diabetes mellitusen_US
dc.typeArticleen_US

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