Effect of nepafenac 0.1% on retinal thickness after cataract surgery in patients without risk factors for cystoid macular edema

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dc.authorid0000-0003-4468-3985
dc.authorid0000-0002-8249-2621
dc.contributor.authorŞahin, Asena Keleş
dc.contributor.authorKükner, Ahmet Şahap
dc.contributor.authorUlaş, Fatih
dc.contributor.authorDoğan, Ümit
dc.date.accessioned2021-06-23T19:53:46Z
dc.date.available2021-06-23T19:53:46Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAIM: To evaluate the effect of topical preoperative nepafenac 0.1% treatment on postoperative macular edema using optical coherence tomography (OCT) after uncomplicated cataract surgery. METHODS: Ninety eyes of 90 patients without any risk factors were included in the study. The patients were assigned to three groups: group 1, treated with topical prednisolone acetate 1%; group 2, treated with topical nepafenac 0.1% in addition to prednisolone acetate (1%); and group 3, those who started receiving nepafenac 0.1% treatment 3d prior to surgery and continued the treatment postoperatively in addition to prednisolone acetate (1%). Central retinal thickness (CRT) and macular volume values were recorded using OCT at weeks 3 and 6. RESULTS: The increases in macular volume in the central 1 mm area after 3 and 6wk were significantly lower in patients who used prophylactic topical nepafenac preoperatively (group 3) compared with those in group 1 (P=0.028 and 0.008, respectively). No significant differences in the increase in macular volume and CRT were noted between groups 2 and 3 (P>0.05). In group 1, the increases in macular volume in the central 3 mm area at weeks 3 and 6 were significantly higher than that in group 2 and 3 (3rd week, P=0.004; 6th week, P=0.005). CONCLUSION: Nepafenac 0.1% treatment in addition to topical steroids after uncomplicated cataract surgery reduce the increase in macular volume in the early postoperative period.en_US
dc.identifier.citationŞahin AK, Kükner AŞ, Ulaş F, Doğan Ü. Effect of nepafenac 0.1% on retinal thickness after cataract surgery in patients without risk factors for cystoid macular edema. Int J Ophthalmol 2020;13(12):1901-1907
dc.identifier.doi10.18240/ijo.2020.12.09
dc.identifier.endpage1907en_US
dc.identifier.issn2222-3959
dc.identifier.issn2227-4898
dc.identifier.issue12en_US
dc.identifier.pmid33344188en_US
dc.identifier.scopus2-s2.0-85096755240en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1901en_US
dc.identifier.urihttps://doi.org/10.18240/ijo.2020.12.09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10239
dc.identifier.volume13en_US
dc.identifier.wosWOS:000596627600009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.institutionauthorDoğan, Ümit
dc.language.isoenen_US
dc.publisherIjo Pressen_US
dc.relation.ispartofInternational Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCataract Surgeryen_US
dc.subjectCystoid Macular Edemaen_US
dc.subjectNepafenacen_US
dc.subjectOptic Coherence Tomographyen_US
dc.subjectRetinal Thicknessen_US
dc.titleEffect of nepafenac 0.1% on retinal thickness after cataract surgery in patients without risk factors for cystoid macular edemaen_US
dc.typeArticleen_US

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