Evaluation of cardiac functions with tissue doppler imaging in prediabetic subjects

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Küçük Resim

Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Korean Soc Cardiology

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background and Objectives: The aim of the present study was to evaluate left ventricle systolic and diastolic function, using tissue Doppler echocardiography (TDE), in relation to blood glucose status in prediabetic patients who had no evidence of heart disease by conventional echocardiography (CE). Subjects and Methods: We included 60 patients (30 female, 30 male) and 20 healthy controls (10 male, 10 female). All participants were randomised into four groups according to their oral glucose tolerance test. Group-I consisted of those patients who had only impaired fasting glucose (IFG). group-II consisted of patients who had only impaired glucose tolerance (IGT) and group-III consisted of patients who had both IFG and IGT, that is so-called combined glucose intolerance. Group-IV included the healthy controls. All subjects underwent both CE and TDE. Results: No significant differences were found among the four groups in terms of CE. There was no significant difference between group-IV and group-I with respect to the early peak diastolic velocity (Ea) of medial mitral annulus (11.65 +/- 0.66 vs. 9.72 +/- 1.58, p>0.05), whereas a statistically significant difference was found between group-IV and group-II (11.65 +/- 0.66 vs. 9.06 +/- 1.07, p<0.001) and between group-IV and group-III (11.65 +/- 0.66 vs. 9.74 +/- 1.09, p<0.05). Conclusion: Diastolic myocardial dysfunction in prediabetic patients may be identified by quantitative TDE before the appearance of CE indices of myocardial dysfunction.

Açıklama

Anahtar Kelimeler

Type 2 diabetes mellitus, Diabetic cardiomyopathies, Tissue Doppler imaging, Glucose intolerance

Kaynak

Korean Circulation Journal

WoS Q Değeri

N/A

Scopus Q Değeri

Q2

Cilt

43

Sayı

2

Künye