Dermatofibrosarcoma protuberans: a rare malignancy

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dc.authorid0000-0002-6839-2632
dc.authorid0000-0001-6768-1275
dc.authorid0000-0001-5588-0306
dc.authorid0000-0001-7965-6229
dc.contributor.authorÜyetürk, Ümmügül
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorDüzcü, Selma Erdoğan
dc.contributor.authorKüçüköztaş, Nadire
dc.contributor.authorYılmaz, Fahri
dc.date.accessioned2021-06-23T19:49:03Z
dc.date.available2021-06-23T19:49:03Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor characterized by protuberant growth pattern of skin and subcutaneous tissue. The annual incidence is 4.2 per million. It is often seen between the ages of 20-50 years. This study aimed to evaluate the characteristics of patients with DFSP. METHODS Patients who visited our clinic were retrospectively evaluated. RESULTS All patients were females and the median age was 42 (29-60) years. The evaluated tumor sites were observed in the body/trunk in one patient, at the hip in two, and at the proximal lower extremity in two. Surgical excision was done in all of them as initial treatment. Re-excision was needed in three patients. One of the patients underwent punch biopsy for diagnosis and surgical removal of the tumor with a negative surgical margin. One of the patients underwent radiotherapy. The median follow-up time was 10 (6-26) months. During the median follow-up, there was no local recurrence or metastasis. CONCLUSION As initial treatment, it is important to surgically remove tumors that had no distant metastasis. Positive or near surgical margins should be resected again. If a negative surgical margin cannot be achieved, radiotherapy should be used as the treatment. Imatinib mesylate is used for treatment in unresectable, recurrent, and/or metastatic tumors.en_US
dc.identifier.doi10.5505/tjo.2017.1635
dc.identifier.endpage152en_US
dc.identifier.issn1300-7467
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85038355602en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage148en_US
dc.identifier.trdizinid270498en_US
dc.identifier.urihttps://doi.org/10.5505/tjo.2017.1635
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9341
dc.identifier.volume32en_US
dc.identifier.wosWOS:000424788200003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÜyetürk, Ümmügül
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorDüzcü, Selma Erdoğan
dc.institutionauthorKüçüköztaş, Nadire
dc.institutionauthorYılmaz, Fahri
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Onkoloji Dergisi-Turkish Journal Of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDermatofibrosarcoma Protuberansen_US
dc.subjectImatiniben_US
dc.subjectRadiotherapyen_US
dc.subjectSurgeryen_US
dc.titleDermatofibrosarcoma protuberans: a rare malignancyen_US
dc.typeArticleen_US

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