Comparison of topical tramadol and ketamine in pain treatment after tonsillectomy

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dc.authorid0000-0002-1630-2033en_US
dc.contributor.authorTekelioğlu, Ümit Yaşar
dc.contributor.authorApuhan, Tayfun
dc.contributor.authorAkkaya, Akcan
dc.contributor.authorDemirhan, Abdullah
dc.contributor.authorYıldız, İsa
dc.contributor.authorŞimşek, Tuğçe
dc.contributor.authorGök, Üzeyir
dc.contributor.authorKoçoğlu, Hasan
dc.date.accessioned2021-06-23T19:34:34Z
dc.date.available2021-06-23T19:34:34Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives/Aim The primary objective of this study is to evaluate the effects of topically applied ketamine or tramadol on early postoperative pain scores in children undergoing tonsillectomy. The secondary aim of the study is to assess nausea, vomiting, difficulty in swallowing, and sore throat characteristics of the patients. Background Tonsillectomy surgery is frequently associated with postoperative pain, which usually requires substantial consumption of analgesics including opioids. Safe and effective post-tonsillectomy pain control is still a clinical dilemma, in spite of the use of various surgical and anesthetic techniques. Methods A total of 60 children, aged between 4 and 10years, scheduled for tonsillectomy, were randomly assigned to one of three groups. Study drugs were administered to both tonsillar fossae for 5min. In 5ml artificial saliva, Group K (n=20) received 0.4ml (20mg) ketamine and Group T (n=20) received 0.8ml tramadol HCl solution. Group C (n=20) received only 5ml saline as a control. Ramsay Sedation Scale and FACES PRS Score, nausea, vomiting, difficulty in swallowing, and sore throat were evaluated. Results There was no difference among the groups in terms of baseline characteristics, including age, sex, and ASA profile (0.05 for all). Systolic blood pressure, diastolic blood pressure, mean blood pressure, heart rate, respiratory rate, and saturation of peripheral oxygen (SpO2) values were not significantly different among the groups in all time points (0.05 for all). There was a statistically significant difference among the groups according to Ramsay Sedation Scales in 40th minute (P<0.001). There were statistically significant differences among the groups in terms of Wong-Baker FACES Pain Rating Scale Score in all time points (P<0.004 for all). There was a statistically significant difference among the groups in terms of rescue analgesia necessity in 5th and 10th minute (P<0.001 and P=0.003). There was a statistically significant difference among the groups in terms of sore throat in 5th and 10th minute (P<0.001 for both). Neither rescue analgesia necessity nor sore throat characteristics was different between the Group T and Group K in all time points. Conclusion Topical tramadol and ketamine seem to be safe, effective, and easy analgesic approach for decreasing tonsillectomy pain.en_US
dc.identifier.doi10.1111/pan.12148
dc.identifier.endpage501en_US
dc.identifier.issn1155-5645
dc.identifier.issn1460-9592
dc.identifier.issue6en_US
dc.identifier.pmid23521170en_US
dc.identifier.scopus2-s2.0-84877578827en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage496en_US
dc.identifier.urihttps://doi.org/10.1111/pan.12148
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7555
dc.identifier.volume23en_US
dc.identifier.wosWOS:000318440900004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTekelioğlu, Ümit Yaşar
dc.institutionauthorApuhan, Tayfun
dc.institutionauthorAkkaya, Akcan
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorYıldız, İsa
dc.institutionauthorŞimşek, Tuğçe
dc.institutionauthorGök, Üzeyir
dc.institutionauthorKoçoğlu, Hasan
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatric Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTonsillectomyen_US
dc.subjectPostoperative Painen_US
dc.subjectTopical Administrationen_US
dc.subjectTramadolen_US
dc.subjectKetamineen_US
dc.subjectPediatricsen_US
dc.titleComparison of topical tramadol and ketamine in pain treatment after tonsillectomyen_US
dc.typeArticleen_US

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