Concha bullosa surgery and the distribution of human olfactory neuroepithelium

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dc.contributor.authorApuhan, Tayfun
dc.contributor.authorYıldırım, Yavuz Selim
dc.contributor.authorŞimşek, Tuğçe
dc.contributor.authorYılmaz, Fahrettin
dc.contributor.authorYılmaz, Fahri
dc.date.accessioned2021-06-23T19:34:45Z
dc.date.available2021-06-23T19:34:45Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractIn bullous middle turbinate surgery, controversy exists over which side of the bullous middle turbinate should be removed, as the distribution of human olfactory neuroepithelium is unclear. This study evaluated whether the middle turbinate tissue of patients undergoing endoscopic concha bullosa surgery contains functional olfactory epithelium. This prospective clinical study was conducted in tertiary referable center. It detected 70 conchae bullosa in 48 patients with sinonasal symptoms, who underwent paranasal computed tomography (CT) that showed pneumatization of the middle concha. All samples were obtained under general anesthesia. Three samples were obtained from each bullous middle turbinate: one each from the anterior, medial, and lateral portions. The mucosa from each sample was stained with olfactory marker protein (OMP). In total, 210 middle turbinate samples were taken from 48 patients during endoscopic surgery for conchae bullosa. The patients were 22 females and 26 males. Of the 70 conchae bullosa, OMP-stained nerve tissue was found in the lateral, anterior and medial aspects of 57 (81.4 %), 42 (60.0 %) and 23 (32.8 %) of the bullous middle turbinates, respectively. OMP-stained nerve tissue was found in 122 (58.1 %) of the 210 bullous middle turbinate tissue samples. OMP-stained nerve tissue was found on the lateral surface of the bullous middle turbinate more often than the medial surface. Therefore, during the concha bullosa surgery, OMP-stained nerve tissue found at least in the medial part of concha, suggested that the opening of the medial part of middle concha.en_US
dc.identifier.doi10.1007/s00405-012-2173-6
dc.identifier.endpage957en_US
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue3en_US
dc.identifier.pmid22941439en_US
dc.identifier.scopus2-s2.0-84878359794en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage953en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-012-2173-6
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7615
dc.identifier.volume270en_US
dc.identifier.wosWOS:000315443000023en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorApuhan, Tayfun
dc.institutionauthorŞimşek, Tuğçe
dc.institutionauthorYılmaz, Fahri
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConcha Bullosa Surgeryen_US
dc.subjectOlfactory Neuroepitheliumen_US
dc.subjectOlfactory Mucosaen_US
dc.subjectConcha Bullosaen_US
dc.subjectMiddle Turbinateen_US
dc.subjectOMPen_US
dc.subjectEndoscopic Surgeryen_US
dc.titleConcha bullosa surgery and the distribution of human olfactory neuroepitheliumen_US
dc.typeArticleen_US

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