Comparison of two anticoagulants for pain associated with platelet-rich plasma injections

dc.authorid0000-0001-9077-2976
dc.contributor.authorGörgü, Metin
dc.contributor.authorGökkaya, Ali
dc.contributor.authorDoğan, Ali
dc.date.accessioned2021-06-23T19:55:00Z
dc.date.available2021-06-23T19:55:00Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground and Aim Platelet-rich plasma (PRP) has long been used in skin rejuvenation and hair loss treatment. Some patients require multiple intradermal injections into the face and scalp, and the way in which these patients process and experience pain differs, depending on the patient. Minimizing pain and discomfort during nonsurgical procedures is essential for patient satisfaction. In our experience, the use of acid citrate dextrose-A (ACD-A) as an anticoagulant caused more patient discomfort than did sodium citrate (Na-citrate) among patients who underwent facial rejuvenation with PRP. The aim of the present study was to evaluate patient-related discomfort in PRP sessions using two different anticoagulants. Materials and Methods This clinical trial included 10 patients who received facial PRP injections for facial rejuvenation and 10 patients who received PRP injections in their scalps for hair loss. On the application area, half the surface was treated with Na-citrate PRP injections, and the other half was treated with the same amount of ACD-A PRP injections. Neither the doctors who applied the treatment nor the patients were given information about which anticoagulant was used in each area. Immediately after the procedure, the patients were asked to score their pain on each side of the application area on a scale of 1-10 using a visual analog scale (VAS). Results PRP injections using Na-citrate as an anticoagulant caused less discomfort on both the face and scalp as compared with that of ACD-A. The outcome was statistically significant. Conclusion Anticoagulants used in PRP preparation affected patients' pain perceptions during the injections. The sensation of pain with PRP prepared with Na-citrate as an anticoagulant was lower than that of PRP prepared with ACD-A. Further studies are required to evaluate the correlation between anticoagulants used for PRP preparation and pain feelings during injections.en_US
dc.identifier.doi10.1007/s00266-019-01541-z
dc.identifier.endpage961en_US
dc.identifier.issn0364-216X
dc.identifier.issn1432-5241
dc.identifier.issue3en_US
dc.identifier.pmid31722064en_US
dc.identifier.scopus2-s2.0-85074996619en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage955en_US
dc.identifier.urihttps://doi.org/10.1007/s00266-019-01541-z
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10702
dc.identifier.volume44en_US
dc.identifier.wosWOS:000496227400004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGörgü, Metin
dc.institutionauthorGökkaya, Ali
dc.institutionauthorDoğan, Ali
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAesthetic Plastic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPRPen_US
dc.subjectPlatelet-rich Plasmaen_US
dc.subjectAnticoagulanten_US
dc.subjectPainen_US
dc.titleComparison of two anticoagulants for pain associated with platelet-rich plasma injectionsen_US
dc.typeArticleen_US

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