The measurement of wound tensile strength and the effect of PRP on wound tensile force: An experimental investigation on rabbits

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dc.authorid0000-0002-9062-7645en_US
dc.authorid0000-0003-2710-9615en_US
dc.authorid0000-0001-9077-2976en_US
dc.contributor.authorGökkaya, Ali
dc.contributor.authorGörgü, Metin
dc.contributor.authorKızılkan, Jehat
dc.contributor.authorKaranfil, Ertuğrul
dc.contributor.authorDoğan, Ali
dc.date.accessioned2023-05-26T11:52:55Z
dc.date.available2023-05-26T11:52:55Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionThis project was supported by the BAP (Scientific Research Projects) unit of Abant Izzet Baysal University (Project No: BAP2017.08.18.1178).en_US
dc.description.abstractPlatelets in PRP are used for their functions in the initiation and regulation of the wound healing process and are used for the repair of injured tissues and the rejuvenation of healthy tissues. In this study, we evaluated the effect of a single dose platelet-rich plasma on skin wound healing and we demonstrated the effect of platelet-rich plasma on skin wound healing by measuring changes in the wound tensile strength. Material and methods: A total of 8 incisions, each 3 cm long, were made on the back skin on both sides of the vertebral column of 12 rabbits. After suturing their backs with staples, platelet rich plasma (PRP) was injected into the edges of the wounds on the left side and saline solution (saline) was injected into the edges of the wounds on the right side. The tensile force that causes wounds to rupture by applying tension was measured on the 7th, 14th, 21st, and 28th days with the help of a special home-designed device. Results: The mean PRP enrichment was 3.19 fold over peripheral blood. The saline to PRP tensile strength ratios on the 7th, 14th, 21st, and 28th days were calculated as 75.7%, 104.0%, 105.3% and 86.5%, respectively. Overall, the difference in the tensile strength for wounds that had received saline or PRP was in-significant. Conclusion: The application of PRP increases the tensile strength of the wound in the early period. It is possible to measure the tensile strength precisely in in vivo studies with economical home-designed devices.en_US
dc.description.sponsorshipBAP (Scientific Research Projects) unit of Abant Izzet Baysal University [BAP2017.08.18.1178]en_US
dc.identifier.citationGökkaya, A., Görgü, M., Kızılkan, J., Karanfil, E., & Doğan, A. (2022). The measurement of wound tensile strength and the effect of PRP on wound tensile force: an experimental investigation on rabbits. Journal of Plastic Surgery and Hand Surgery, 56(1), 38-46.en_US
dc.identifier.doi10.1080/2000656X.2021.1914637
dc.identifier.endpage46en_US
dc.identifier.issn2000-656X
dc.identifier.issn2000-6764
dc.identifier.issue1en_US
dc.identifier.pmid34106813en_US
dc.identifier.scopus2-s2.0-85107636161en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage38en_US
dc.identifier.urihttp://dx.doi.org/10.1080/2000656X.2021.1914637
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10973
dc.identifier.volume56en_US
dc.identifier.wosWOS:000659445700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGökkaya, Ali
dc.institutionauthorGörgü, Metin
dc.institutionauthorKaranfil, Ertuğrul
dc.institutionauthorDoğan, Ali
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Plastic Surgery and Hand Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlatelet-Rich Plasmaen_US
dc.subjectPRPen_US
dc.subjectTensile Strengthen_US
dc.subjectWound Healingen_US
dc.titleThe measurement of wound tensile strength and the effect of PRP on wound tensile force: An experimental investigation on rabbitsen_US
dc.typeArticleen_US

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