Epidemiologic and clinical characteristics of neonates with late?onset COVID?19: 1?year data of Turkish Neonatal Society

Basit Öğe Kaydı
dc.authorid0000-0002-3677-1582en_US
dc.authorid0000-0001-6859-6689en_US
dc.authorid0000-0002-1861-2262en_US
dc.authorid0000-0003-0760-0773en_US
dc.authorid0000-0003-3869-6288en_US
dc.authorid0000-0002-1861-2262en_US
dc.contributor.authorAkın, İlke Mungan
dc.contributor.authorKanburoğlu, Mehmet Kenan
dc.contributor.authorTayman, Cüneyt
dc.contributor.authorÖncel, Mehmet Yekta
dc.contributor.authorİmdadoğlu, Temuçin
dc.contributor.authorDilek, Mustafa
dc.date.accessioned2023-09-11T06:35:42Z
dc.date.available2023-09-11T06:35:42Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe literature on neonates with SARS-CoV-2 is mainly concerned with perinatal cases, and scanty data are available about environmentally infected neonates. To fill knowledge gaps on the course and prognosis of neonatal cases, we analyzed 1-year data from the Turkish Neonatal Society in this prospective cohort study of neonates with postnatal transmission. Data from 44 neonatal intensive care units (NICUs), of neonates with positive RT-PCR results at days 5-28 of life, were extracted from the online registry system and analyzed. Of 176 cases, most were term infants with normal birth weight. Fever was the most common symptom (64.2%), followed by feeding intolerance (25.6%), and cough (21.6%). The median length of hospitalization was 9 days, with approximately one quarter of infants receiving some type of ventilatory support. Myocarditis (5.7%) was the most common complication during follow-up. Among the clinical findings, cough (odds ratio [OR]: 9.52, 95% confidence interval [CI]: 4.17-21.71), tachypnea (OR: 26.5, 95% CI: 9.59-73.19), and chest retractions (OR: 27.5, 95% CI: 5.96-126.96) were associated with more severe clinical disease. Also, there were significant differences in the C-reactive protein level, prothrombin time (PT), partial thromboplastin time, international normalized ratio, and days in the NICU (p = 0.002, p = 0.012, p = 0.034, p = 0.008, and p < 0.001, respectively) between patients with mild-moderate and severe-critical presentations. A PT above 14 s was a significant predictor of severe/critical cases, with a sensitivity of 64% and specificity of 73%. Conclusions: Our data showed that late-onset COVID-19 infection in neonates who need hospitalization can be severe, showing associations with high rates of ventilatory support and myocarditis. Cough, tachypnea, and retractions on admission suggest a severe disease course.en_US
dc.identifier.citationAkin, I. M., Kanburoglu, M. K., Tayman, C., Oncel, M. Y., Imdadoglu, T., Dilek, M., ... & Koc, E. (2022). Epidemiologic and clinical characteristics of neonates with late-onset COVID-19: 1-year data of Turkish Neonatal Society. European journal of pediatrics, 181(5), 1933-1942.en_US
dc.identifier.doi10.1007/s00431-021-04358-8
dc.identifier.endpage1942en_US
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.issue5en_US
dc.identifier.pmid35061093en_US
dc.identifier.scopus2-s2.0-85123408502en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1933en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s00431-021-04358-8
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11687
dc.identifier.volume181en_US
dc.identifier.wosWOS:000745396400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDilek, Mustafa
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSARS-CoV-2en_US
dc.subjectCOVID-19en_US
dc.subjectNewbornen_US
dc.subjectPostnatalen_US
dc.subjectManagementen_US
dc.titleEpidemiologic and clinical characteristics of neonates with late?onset COVID?19: 1?year data of Turkish Neonatal Societyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
ilke-mungan-akın.pdf
Boyut:
895.86 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu