Embolization of peripheral vascular malformations with ethylene vinyl alcohol copolymer (Onyx)

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dc.authorid0000-0002-4179-4324en_US
dc.authorid0000-0003-4531-6466en_US
dc.authorid0000-0003-3503-9207en_US
dc.authorid0000-0002-3180-6029
dc.authorid0000-0002-1795-9635
dc.contributor.authorNuman, Furuzan
dc.contributor.authorÖmeroğlu, Alp
dc.contributor.authorKara, Batuhan
dc.contributor.authorCantaşdemir, Murat
dc.contributor.authorAdaletli, İbrahim
dc.contributor.authorKantarcı, Fatih
dc.date.accessioned2021-06-23T19:17:53Z
dc.date.available2021-06-23T19:17:53Z
dc.date.issued2004
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPURPOSE: To demonstrate the feasibility and preliminary efficacy of endovascular embolization of peripheral congenital vascular malformations (VMs) with use of a nonadhesive liquid embolic agent, Onyx. MATERIALS AND METHODS: Nine patients with a mean age of 20.8 years had local low-flow (n = 4), local high-flow (n = 3), or diffuse high-flow (n = 2) VMs located in the upper or lower extremities. In all patients, endovascular embolization was performed via the superselective catheterization of arterial feeders of VMs with use of microcatheters in a coaxial technique. A total of 15 embolization procedures were performed with Onyx, which was composed of 6%, 8%, or 20% ethylene vinyl alcohol copolymer dissolved in dimethyl sulfoxide. RESULTS: In two of four patients with local low-flow VMs, the lesions were embolized completely. In the other two patients with local low-flow VMs, embolizations were incomplete. The remaining five high-flow lesions of local (n = 3) or diffuse (n = 2) types were also embolized incompletely. In all patients with local low-flow VMs and in one patient with a local high-flow VM, clinical signs and symptoms were resolved significantly. Other patients did show clinical benefit from embolization to varying degrees. CONCLUSION: In our experience in a limited number of cases, Onyx promises and provides important advantages over conventional embolic agents in the endovascular transcatheter embolization of congenital peripheral VMs. However, as with other embolic agents, it is far from perfect.en_US
dc.identifier.doi10.1097/01.RVI.0000130862.23109.52
dc.identifier.endpage946en_US
dc.identifier.issn1051-0443
dc.identifier.issue9en_US
dc.identifier.pmid15361561en_US
dc.identifier.scopus2-s2.0-4544261044en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage939en_US
dc.identifier.urihttps://doi.org/10.1097/01.RVI.0000130862.23109.52
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5573
dc.identifier.volume15en_US
dc.identifier.wosWOS:000227678600006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖmeroğlu, Alp
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofJournal Of Vascular And Interventional Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVascular Malformationsen_US
dc.subjectEmbolization
dc.subjectPeripheral
dc.subjectEthylene
dc.titleEmbolization of peripheral vascular malformations with ethylene vinyl alcohol copolymer (Onyx)en_US
dc.typeArticleen_US

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