Effect of fasting on choroidal thickness and Its diurnal variation

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dc.authorid0000-0003-2544-3580en_US
dc.authorid0000-0003-4468-3985en_US
dc.authorid0000-0002-8249-2621
dc.authorid0000-0001-8305-6600
dc.contributor.authorUyar, Enes
dc.contributor.authorDoğan, Ümit
dc.contributor.authorUlaş, Fatih
dc.contributor.authorÇelebi, Serdal
dc.date.accessioned2021-06-23T19:53:46Z
dc.date.available2021-06-23T19:53:46Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: The aim of this study was to assess the effect of Ramadan fasting on choroidal thickness (CT) and its associated diurnal variations using spectral domain optic coherence tomography. Materials and Methods: Ocular measurements were performed on a single eye of 87 healthy individuals. Eyes were evaluated twice a day around 8.00 a.m. and 4.00 p.m. during Ramadan. Evaluations were repeated at the same time of the day, 1 month following Ramadan on the same subjects. Measurements of choroidal and retinal thickness were performed at central, temporal and nasal segments. Results: The comparison of measurements revealed that temporal CT at 8.00 a.m. and foveal, temporal and nasal CTs at 4.00 p.m. were significantly reduced during fasting (p values were 0.005, <0.001, 0.001 and 0.046, respectively). Mean changes of CTs during fasting were 14.76 +/- 16.01, 9.90 +/- 19.57 and 8.10 +/- 16.81 mu m at the fovea, temporal and nasal segments, respectively. However, CTs at non-fasting conditions were measured as 6.13 +/- 12.93, 3.78 +/- 15.23 and 5.05 +/- 13.60 mu m, respectively. In comparison, diurnal variations of foveal and temporal CTs during fasting were significantly higher than the controls (p values were <0.001 and 0.004, respectively). Additionally, retinal thicknesses during fasting were significantly reduced compared to the controls in all segments measured at 4.00 p.m. (p for all values <0.05) Conclusions: The results of the present study revealed that fasting and dehydration caused a reduction of the choroidal and retinal thicknesses. Likewise, they are also responsible for the increased diurnal variation of CTs. Therefore, early hours of the day may be preferred to evaluate retinal and choroidal thicknesses during Ramadan to avoid the effects of dehydration on the measurement results.en_US
dc.identifier.doi10.1080/02713683.2019.1584677
dc.identifier.endpage700en_US
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue7en_US
dc.identifier.pmid30777786en_US
dc.identifier.scopus2-s2.0-85062470425en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage695en_US
dc.identifier.urihttps://doi.org/10.1080/02713683.2019.1584677
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10236
dc.identifier.volume44en_US
dc.identifier.wosWOS:000587758200002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUyar, Enes
dc.institutionauthorDoğan, Ümit
dc.institutionauthorUlaş, Fatih
dc.institutionauthorÇelebi, Serdal
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChoroidal Thicknessen_US
dc.subjectDiurnal Variationen_US
dc.subjectFastingen_US
dc.subjectOptic Coherence Tomographyen_US
dc.subjectRetinal Thicknessen_US
dc.titleEffect of fasting on choroidal thickness and Its diurnal variationen_US
dc.typeArticleen_US

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