Effect of ELF magnetic fields on lipid peroxidation, sperm count, p53, and trace elements
Küçük Resim Yok
Tarih
2006
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Some epidemiological and laboratory studies suggest a possible connection between extremely low-frequency (ELF) magnetic fields and certain illnesses, such as cancer, immune suppression, as well as reproductive toxic effects and abnormalities. Therefore, the aim of this study was to investigate the effects of ELF magnetic fields (1.35 mT) on sperm count, malondialdehyde concentration, the histology of such organs as the testes, brain, liver, and kidney tissues, p53 immunoreactivity of bone marrow, and the serum concentrations of Cu2+, Zn2+, Mn2+, and Fe 3+ in rats. Material/Methods: Sixteen Sprague-Dawley male rats were divided into two groups. The rats in the experimental group were exposed to an ELF magnetic field 2 hr/day for 2 months (7 days a week). The rats in the control group were not exposed to the ELF magnetic field. The exposure was performed in a Faraday cage (130x65x80 cm) with grounded shielding against the electric component. The Mann-Whitney U-test was used for the statistical analysis of the data. Results: Magnetic field measurements showed that, under the experimental conditions, the magnetic fieldexposure system produced a stable flux density of 1.35±0.018 mT and a stable frequency of 50 Hz, with negligible harmonics and no transients. However, no statistically significant alteration was observed in the parameters measured in this study except in Mn2+ concentrations (p<0.001). Conclusions: The present study found no evidence of an adverse effect of ELF magnetic fields on the measured parameters except for significantly increased Mn2+ concentrations (p<0.001). © Med Sci Monit, 2006.
Açıklama
Anahtar Kelimeler
ELF magnetic field, Histology, Malondialdehyde, p53, Sperm, Trace elements
Kaynak
Medical Science Monitor
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
12
Sayı
11
