The effect of desflurane on postoperative olfactory memory

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dc.authorid0000-0002-1706-4444
dc.authorid0000-0002-6223-4254
dc.authorid0000-0002-2311-6431
dc.authorid0000-0002-0363-9307
dc.contributor.authorYıldız, İsa
dc.contributor.authorBayır, Hakan
dc.contributor.authorSağlam, İbrahim
dc.contributor.authorŞereflican, Murat
dc.contributor.authorBilgi, Murat
dc.contributor.authorYurttaş, Veysel
dc.contributor.authorDemirhan, Abdullah
dc.contributor.authorKoçoğlu, Hasan
dc.date.accessioned2021-06-23T19:43:35Z
dc.date.available2021-06-23T19:43:35Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: In this study, we investigated the effects of desflurane 6%, on olfactory memory. PATIENTS AND METHODS: This is a prospective clinical study performed with 40 patients aged 18-60 who had elective surgery and American Society of Anesthesiologists (ASA) physical status I-III. The Brief Smell Identification Test (BSIT) was used for evaluating patients' olfactory memories before and after the surgery. Patients received standard general anesthesia protocol and routine monitoring. For induction, 1.5 mg/kg of fentanyl, 2 mg/kg of propofol, and 0.5 mg/kg of rocuronium bromide were administered. Anesthesia was maintained with the inhalational of anesthetic desflurane (6%). The scores are recorded 30 minutes before the surgery and when the Aldrete Recovery Score reached 10 in the postoperative period. Preoperative and postoperative results were compared and p-values <0.05 were considered statistically significant. RESULTS: The patients' mean age was 41.1 +/- 12.0. Preoperative total correct answer rate to odorous substances was 92.7%, and postoperative rate was 92.1%. Percentage of the odor substance identification by the patients revealed no statistically significant difference when pre and post-operative rates have been compared (p-value > 0.05). CONCLUSIONS: We have observed for the first time in the literature that general anesthesia using desflurane (6%) did not affect short-term olfactory memory. Further studies will be necessary to confirm our findings with larger sample size.en_US
dc.identifier.endpage2167en_US
dc.identifier.issn1128-3602
dc.identifier.issue10en_US
dc.identifier.pmid27249619en_US
dc.identifier.scopus2-s2.0-84984856777en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2163en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8809
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000382459500034
dc.identifier.volume20en_US
dc.identifier.wosWOS:000382459500034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldız, İsa
dc.institutionauthorBayır, Hakan
dc.institutionauthorSağlam, İbrahim
dc.institutionauthorŞereflican, Murat
dc.institutionauthorBilgi, Murat
dc.institutionauthorYurttaş, Veysel
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorKoçoğlu, Hasan
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnaesthetics Volatileen_US
dc.subjectDesfluraneen_US
dc.subjectOlfactory Memoryen_US
dc.subjectSmellen_US
dc.titleThe effect of desflurane on postoperative olfactory memoryen_US
dc.typeArticleen_US

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