Elevated neurotensin levels among obese adolescents may be related to emotion dysregulation and impulsivity: A cross-sectional, case-control study

dc.authorid0000-0002-0508-0594en_US
dc.authorid0000-0002-3002-480Xen_US
dc.authorid0000-0002-3412-9879en_US
dc.authorid0000-0003-3440-3513en_US
dc.authorid0000-0002-7506-061Xen_US
dc.authorid0000-0001-5207-6240en_US
dc.contributor.authorÖzyurt, Gonca
dc.contributor.authorCingöz, Gülten
dc.contributor.authorÖztürk, Yusuf
dc.contributor.authorKüme, Tuncay
dc.contributor.authorDündar, Bumin Nuri
dc.contributor.authorTufan, Ali Evren
dc.date.accessioned2023-09-01T13:08:51Z
dc.date.available2023-09-01T13:08:51Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionThis work was supported by the scientific research project comittee of Izmir Katip Celebi University by grant number 2017-TDUTIPF-0037.en_US
dc.description.abstractBackground. In this study, we aimed to evaluate the serum neurotensin (NT) levels and their relationships with self-reported anxiety, emotion regulation skills and impulsivity in healthy and obese adolescents. Methods. Adolescents who gained weight between 12-17 years of age and who were above the 95th percentile (p) for body mass index (BMI)>95p were compared with age-and gender-matched healthy adolescents with a BMI of 3-85 p. Anthropometric measurements were performed, and serum NT levels were analyzed with ELISA method in all participants. Barrat Impulsivity Scale-11 (BIS-11), Screen for Child Anxiety Related Disorders (SCARED) and Difficulties in Emotion Regulation Scale (DERS) were used for evaluating self-reported impulsivity, anxiety and emotion regulation. MANOVA with follow-up univariate ANOVAs (Bonferroni corrected) were used for group comparisons. P was set at 0.05 (two-tailed). Results. Sixty-five obese and 65 healthy adolescents were included in the study. In the obese group, NT levels were significantly elevated compared to the control group. Self-reported emotion-regulation difficulties, anxiety and impulsivity were significantly elevated among obese adolescents. Serum NT levels among the obese group were positively correlated with emotion dysregulation and impulsivity scores. Conclusions. In this study, we found emotional dysregulation, anxiety, impulsivity, and serum NT levels were significantly elevated among obese adolescents compared to controls. NT levels in the obese group correlated with impulsivity and emotion dysregulation. Further studies should evaluate the potential role of NT in the etiology of psychopathology among adolescents who are obese.en_US
dc.description.sponsorshipscientific research project comittee of Izmir Katip Celebi University [2017-TDUTIPF-0037]en_US
dc.identifier.citationÖzyurt, G., Cingoz, G., Öztürk, Y., Küme, T., DÜNDAR, B., Tufan, A., & ÇATLI, G. (2022). Elevated neurotensin levels among obese adolescents may be related to emotion dysregulation and impulsivity: a cross-sectional, case-control study. Turkish Journal of Pediatrics, 64(2).en_US
dc.identifier.doi10.24953/turkjped.2021.1437
dc.identifier.endpage264en_US
dc.identifier.issn0041-4301
dc.identifier.issue2en_US
dc.identifier.pmid35611414en_US
dc.identifier.scopus2-s2.0-85130703178en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage255en_US
dc.identifier.trdizinid1138287en_US
dc.identifier.urihttp://dx.doi.org/10.24953/turkjped.2021.1437
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11636
dc.identifier.volume64en_US
dc.identifier.wosWOS:000802228700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖztürk, Yusuf
dc.institutionauthorTufan, Ali Evren
dc.language.isoenen_US
dc.publisherTurkish National Pediatric Societyen_US
dc.relation.ispartofThe Turkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdolescenten_US
dc.subjectAnxietyen_US
dc.subjectEmotion Regulationen_US
dc.subjectPsychometric Propertiesen_US
dc.subjectTurkish Versionen_US
dc.subjectChildrenen_US
dc.titleElevated neurotensin levels among obese adolescents may be related to emotion dysregulation and impulsivity: A cross-sectional, case-control studyen_US
dc.typeArticleen_US

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