Kinetic factors may trigger lesion development in the patients with psoriatic arthritis

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dc.authorid0000-0003-0290-9341en_US
dc.contributor.authorTönük, Şükrü Burak
dc.contributor.authorRamadan, Barış
dc.contributor.authorYorgancıoğlu, Zeynep Rezan
dc.date.accessioned2021-06-23T19:43:00Z
dc.date.available2021-06-23T19:43:00Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBiomechanical factors are likely to play a more sub-stantial role in the pathogenesis of psoriatic arthritis(PsA) compared to other spondyloarthropathies. Thenail, and particularly the lunula, is a frequently trau-matized tissue that is both functionally and histologi-cally integrated with the musculoskeletal system.1Arelationship between the inflammatory enthesealchanges of the distal interphalangeal joint capsuleand nail lesions in patients with PsA was demon-strated using magnetic resonance imaging (MRI).2Entheseal thickening of the digital extensor tendon ismore common in patients with clinical nail diseasecompared to patients without clinical nail disease inboth psoriasis and PsA.3Just as in the Koebner anddeep Koebner phenomena, these results point to thepotential effects of biomechanical factors in the path-ogenesis of psoriasis. It should be noted that psoriat-ic skin lesions most commonly appear on the sacralarea and extensor surfaces of the knee and elbow,where the skin is strained due to the excessive rangeof flexion motion. Another frequently involved site,the scalp, is also a stretched skin tissue. The cervicalspine, which is more mobile during the activities ofdaily living compared to the lumbar region, is proba-bly more frequently involved in PsA compared toother spondyloarthopathies. Radiographic changes ofthe cervical spine are more commonly observed inboth patients with psoriasis and those with PsA com-pared to healthy controls.4The cervical spine may bethe only axial involvement, especially when PsApatients are female and human leukocyte antigen(HLA)-B27 negative.en_US
dc.identifier.doi10.1111/1756-185X.12681
dc.identifier.endpage1034en_US
dc.identifier.issn1756-1841
dc.identifier.issn1756-185X
dc.identifier.issue10en_US
dc.identifier.pmid26179314en_US
dc.identifier.scopus2-s2.0-84995676826en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1032en_US
dc.identifier.urihttps://doi.org/10.1111/1756-185X.12681
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8667
dc.identifier.volume19en_US
dc.identifier.wosWOS:000400672400014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTönük, Şükrü Burak
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Rheumatic Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectActivities of Daily Livingen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectAutoinflammationen_US
dc.subjectBiomechanicsen_US
dc.subjectPsoriasisen_US
dc.subjectPsoriatic Arthritisen_US
dc.titleKinetic factors may trigger lesion development in the patients with psoriatic arthritisen_US
dc.typeArticleen_US

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