In vitro antibacterial and antitumor activities of some medicinal plant extracts, growing in Turkey

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dc.authorid0000-0001-7712-2813en_US
dc.contributor.authorYıldırım, Arzu Birinci
dc.contributor.authorKarakaş, Fatma Pehlivan
dc.contributor.authorTürker, Arzu Uçar
dc.date.accessioned2021-06-23T19:34:23Z
dc.date.available2021-06-23T19:34:23Z
dc.date.issued2013
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractObjective: To investigate antibacterial and antitumor activities of 51 different extracts prepared with 3 types of solvents (water, ethanol and methanol) of 16 different plant species (Ajuga reptans (A. reptans) L., Phlomis pungens (P. pungens) Wild., Marrubium astracanicum, (M. astracanicum) Jacq., Nepeta nuda (N. nuda) L., Stachys annua (S. annua) L., Genista lydia (G. lydia) Boiss., Nuphar lutea (N. lutea) L., Nymphaea alba (N. alba) L., Vinca minor (V. minor) L., Stellaria media (S. media) L., Capsella bursa-pastoris (C. bursa-pastoris) L., Galium spurium (G. spurium) L., Onosma heterophyllum (O. heterophyllum) Griseb., Reseda luteola (R. luteola) L., Viburnum lantana (V. lantana) L. and Mercurialis annua (M. annua) L.) grown in Turkey was conducted. Methods: Antibacterial activity was evaluated with 10 bacteria including Streptococcus pyogenes (S. pyogenes), Staphylococcus aureus (S. aureus), Staphylococcus epidermidis (S. epidermidis), Escheria coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Salmonella typhimurium (S. typhimurium), Serratia marcescens (S. marcescens), Proteus vulgaris (P. vulgaris), Enterobacter cloacae (E. cloacea), and Klebsiella pneumoniae (K. pneumoniae) by using disc diffusion method. Antitumor activity was evaluated with Agrobacterium tumefaciens (A. turnefaciens)-induced potato disc tumor assay. Results: Best antibacterial activity was obtained with ethanolic extract of P. pungens against S. pyogenes. Ethanolic and methanolic extract of N. alba and ethanolic extract of G. lydia also showed strong antibacterial activities. Results indicated that alcoholic extracts especially ethanolic extracts exhibited strong antibacterial activity against both gram-positive and gram-negative bacteria. Best antitumor activity was obtained with methanolic extracts of N. alba and V. lantana (100% tumor inhibition). Ethanolic extract of N. alba, alcoholic extracts of N. lutea, A. reptans and V. minor flowers, methanolic extracts of G. lydia and O. heterophyllum and ethanolic extract of V. lantana and aqueous extract of V. minor leaves exhibited strong tumor inhibitions. Conclusions: In near future works, identification of active components can be studied for plant extracts having strong bioactivity.en_US
dc.identifier.doi10.1016/S1995-7645(13)60106-6
dc.identifier.endpage624en_US
dc.identifier.issn1995-7645
dc.identifier.issue8en_US
dc.identifier.pmid23790332en_US
dc.identifier.scopus2-s2.0-84879220775en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage616en_US
dc.identifier.urihttps://doi.org/10.1016/S1995-7645(13)60106-6
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7490
dc.identifier.volume6en_US
dc.identifier.wosWOS:000322096600005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldırım, Arzu Birinci
dc.institutionauthorKarakaş, Fatma Pehlivan
dc.institutionauthorTürker, Arzu Uçar
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofAsian Pacific Journal Of Tropical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBioassaysen_US
dc.subjectAntibacterialen_US
dc.subjectAntitumoren_US
dc.subjectMedicinal Plantsen_US
dc.titleIn vitro antibacterial and antitumor activities of some medicinal plant extracts, growing in Turkeyen_US
dc.typeArticleen_US

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