Migraine and associated comorbidities are three times more frequent in children with ADHD and their mothers

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dc.authorid0000-0001-5207-6240en_US
dc.authorid0000-0002-2918-7871
dc.authorid0000-0003-2776-6930
dc.authorid0000-0003-2735-4805
dc.contributor.authorKütük, Meryem Özlem
dc.contributor.authorTufan, Ali Evren
dc.contributor.authorGüler, Gülen
dc.contributor.authorYalın, Osman Özgür
dc.contributor.authorAltıntaş, Ebru
dc.date.accessioned2021-06-23T19:49:24Z
dc.date.available2021-06-23T19:49:24Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Attention deficit and hyperactivity disorder (ADHD) is a neuro-developmental disorder related to internalizing and externalizing disorders as well as somatic complaints and disorders. This study was conducted to evaluate the prevalence of headache subtypes, epilepsy, atopic disorders, motion sickness and recurrent abdominal pain among children and adolescents with ADHD and their parents. Methods: In a multi-center, cross-sectional, familial association study using case-control design, treatment na ve children and adolescents between 6 and 18 years of age diagnosed with ADHD according to the DSM-5 criteria as well as age- and gender matched healthy controls and their parents were evaluated by a neurologist and analyzed accordingly. Results: 117 children and adolescents with ADHD and 111 controls were included. Headache disorder diagnosis was common for both patients and healthy controls (59.0% vs. 37.8%), with a significantly elevated rate in the ADHD group (p = 0.002). Migraine was found in 26.0% of ADHD patients and 9.9% of healthy controls. Tension headache was found in 32.4% of ADHD patients and 27.9% of healthy controls. Headache diagnosis was also found to be significantly more common in mothers of children with ADHD than control group mothers (90.5% vs. 36.6%, p < 0.001). Conclusion: Headache diagnoses and specifically migraines were significantly more common among children with ADHD and their mothers, while recurrent abdominal pain was elevated in both parents and ADHD patients. Migraine is an important part of ADHD comorbidity, not only for children but also for mothers. Motion sickness may be reduced among families of ADHD probands. (C) 2018 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.braindev.2018.06.001
dc.identifier.endpage864en_US
dc.identifier.issn0387-7604
dc.identifier.issn1872-7131
dc.identifier.issue10en_US
dc.identifier.pmid29921473en_US
dc.identifier.scopus2-s2.0-85048477394en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage857en_US
dc.identifier.urihttps://doi.org/10.1016/j.braindev.2018.06.001
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9488
dc.identifier.volume40en_US
dc.identifier.wosWOS:000447683300003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKütük, Meryem Özlem
dc.institutionauthorTufan, Ali Evren
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBrain & Developmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMigraineen_US
dc.subjectAttention Deficit and Disruptive Behavior Disordersen_US
dc.subjectTension-Type Headacheen_US
dc.titleMigraine and associated comorbidities are three times more frequent in children with ADHD and their mothersen_US
dc.typeArticleen_US

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