Cardiac autonomic function in healthy young smokers

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dc.authorid0000-0003-3464-3197en_US
dc.authorid0000-0002-3156-1076en_US
dc.contributor.authorErdem, Alim
dc.contributor.authorAyhan, Suzi Selim
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorÖzlü, Mehmet Fatih
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorTosun, Mehmet
dc.contributor.authorGümüştekin, Kenan
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2021-06-23T19:42:37Z
dc.date.available2021-06-23T19:42:37Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe present study examined the heart rate turbulence (HRT) and heart rate variability (HRV) parameters in healthy young smokers (<40years) to assess the effects of smoking on cardiac autonomic function. The study included 75 smokers with a history of habitual smoking for at least 1year (41 males and 34 females; mean age, 29.3 +/- 7.3years) and 30 nonsmokers (hospital staff; 16 males and 14 females; mean age, 29.0 +/- 6.1years). Addiction to smoking was evaluated using the modified Fagerstrom test for nicotine-dependence index (NDI). HRT, HRV, basic clinical and echocardiographic, and Holter test parameters were compared between groups. No significant differences between the two groups were found in the basic clinical and echocardiographic variables. Turbulence onset (TO) was significantly higher in the smoking group than in the controls, and turbulence slope was significantly lower in the smokers, than in the controls (p<0.05). Standard deviation of all normal-to-normal (NN) interval index (SDNNI) was the only HRV parameter that was significantly different between the smoking and control groups (p<0.05). The NDI was positively correlated with the TO (p<0.05). Smoking impairs the baroregulatory function in healthy young smokers, particularly the HRT parameters and SDNNI. Our findings highlight the importance of complete smoking cessation.en_US
dc.identifier.doi10.1177/0748233712468024
dc.identifier.endpage72en_US
dc.identifier.issn0748-2337
dc.identifier.issn1477-0393
dc.identifier.issue1en_US
dc.identifier.pmid23235997en_US
dc.identifier.scopus2-s2.0-84920031599en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage67en_US
dc.identifier.urihttps://doi.org/10.1177/0748233712468024
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8552
dc.identifier.volume31en_US
dc.identifier.wosWOS:000346904600008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorErdem, Alim
dc.institutionauthorAyhan, Suzi Selim
dc.institutionauthorÖztürk, Serkan
dc.institutionauthorÖzlü, Mehmet Fatih
dc.institutionauthorAlçelik, Aytekin
dc.institutionauthorTosun, Mehmet
dc.institutionauthorGümüştekin, Kenan
dc.institutionauthorYazıcı, Mehmet
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofToxicology And Industrial Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSmokingen_US
dc.subjectCardiac Automaticityen_US
dc.subjectNicotine-Dependence Indexen_US
dc.subjectHeart Rate Turbulenceen_US
dc.subjectHeart Rate Variabilityen_US
dc.titleCardiac autonomic function in healthy young smokersen_US
dc.typeArticleen_US

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