Need of cost-effective vaccines in developing countries: what plant biotechnology can offer?

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dc.authorid0000-0002-9861-462Xen_US
dc.authorid0000-0001-6767-2539en_US
dc.contributor.authorWaheed, Mohammad Tahir
dc.contributor.authorSameeullah, Muhammad
dc.contributor.authorKhan, Faheem Ahmed
dc.contributor.authorSyed, Tahira
dc.contributor.authorIlahi, Manzoor
dc.date.accessioned2021-06-23T19:43:57Z
dc.date.available2021-06-23T19:43:57Z
dc.date.issued2016
dc.departmentBAİBÜ, Ziraat Fakültesi, Bahçe Bitkileri Bölümüen_US
dc.description.abstractTo treat current infectious diseases, different therapies are used that include drugs or vaccines or both. Currently, the world is facing an increasing problem of drug resistance from many pathogenic microorganisms. In majority of cases, when vaccines are used, formulations consist of live attenuated microorganisms. This poses an additional risk of infection in immunocompromised patients and people suffering from malnutrition in developing countries. Therefore, there is need to improve drug therapy as well as to develop next generation vaccines, in particular against infectious diseases with highest mortality rates. For patients in developing countries, costs related to treatments are one of the major hurdles to reduce the disease burden. In many cases, use of prophylactic vaccines can help to control the incidence of infectious diseases. In the present review, we describe some infectious diseases with high impact on health of people in low and middle income countries. We discuss the prospects of plants as alternative platform for the development of next-generation subunit vaccines that can be a cost-effective source for mass immunization of people in developing countries.en_US
dc.identifier.doi10.1186/s40064-016-1713-8
dc.identifier.issn2193-1801
dc.identifier.pmid26839758en_US
dc.identifier.scopus2-s2.0-84955491504en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1186/s40064-016-1713-8
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8886
dc.identifier.volume5en_US
dc.identifier.wosWOS:000368877800005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSameeullah, Muhammad
dc.language.isoenen_US
dc.publisherSpringer International Publishing Agen_US
dc.relation.ispartofSpringerplusen_US
dc.relation.publicationcategoryKitap İncelemesi - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiopharmaceuticalsen_US
dc.subjectPlant-Based Vaccinesen_US
dc.subjectAdjuvantsen_US
dc.subjectInfectious Diseasesen_US
dc.subjectDrug Resistant Microorganismsen_US
dc.subjectNext Generation Vaccinesen_US
dc.titleNeed of cost-effective vaccines in developing countries: what plant biotechnology can offer?en_US
dc.typeReview Articleen_US

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