Evaluation of toxoplasma, rubella, and cytomegalovirus serological results in women of childbearing age

dc.authorid0000-0002-6011-7775en_US
dc.authorid0000-0002-5676-6983
dc.authorid0000-0002-7057-2501
dc.contributor.authorAvcıoğlu, Fatma
dc.contributor.authorBehçet, Mustafa
dc.contributor.authorKurtoğlu, Muhammet Güzel
dc.date.accessioned2021-06-23T19:54:10Z
dc.date.available2021-06-23T19:54:10Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: This study aimed to determine the rates of IgG and IgM antibodies against cytomegalovirus, rubella, and Toxoplasma gondii (all of which may cause congenital infections) in women of childbearing age who were admitted to Bolu Abant Izzet Baysal University Training and Research Hospital. METHODS: Between January 2015 and December 2017, Toxoplasma gondii, rubella, and cytomegalovirus IgM and IgG antibody levels were studied using the ELISA method (Architect i2000SR, Abbott, Germany) in patients aged 15 to 45 who attended the obstetrics and gynecology outpatient clinics. Toxoplasma gondii and cytomegalovirus IgG avidity levels were analyzed retrospectively. RESULTS: A total of 13.470 tests were conducted in the laboratory. Seropositivity percentages of IgM antibodies were found to be 1.3%, 0.5%, and 1.6% for Toxoplasma (n = 3607), rubella (n = 3931), and cytomegalovirus (n = 3795), respectively. The seropositivity percentages of IgG antibodies were 22%, 94.2%, and 98.2% for Toxoplasma (n = 702), rubella (n = 693), and cytomegalovirus (n = 679), respectively. Primary infection (acute, recently acquired) was found in 7(35%) patients with low Toxoplasma IgG avidity. One (3%) patient with low cytomegalovirus IgG avidity had a primary infection. CONCLUSION: Toxoplasma gondii seronegativity was found to be high in the region. Therefore, screening women of childbearing age may be important for the prevention of congenital infections caused by Toxoplasma gondii.en_US
dc.identifier.doi10.1590/1806-9282.66.6.789
dc.identifier.endpage793en_US
dc.identifier.issn1806-9282
dc.identifier.issue6en_US
dc.identifier.pmid32696860en_US
dc.identifier.scopus2-s2.0-85088456144en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage789en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.66.6.789
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10447
dc.identifier.volume66en_US
dc.identifier.wosWOS:000551893100017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAvcıoğlu, Fatma
dc.institutionauthorKurtoğlu, Muhammet Güzel
dc.institutionauthorBehçet, Mustafa
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectToxoplasmaen_US
dc.subjectRubellaen_US
dc.subjectCytomegalovirusen_US
dc.subjectImmunoglobulin Gen_US
dc.subjectImmunoglobulin Men_US
dc.titleEvaluation of toxoplasma, rubella, and cytomegalovirus serological results in women of childbearing ageen_US
dc.typeArticleen_US

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