Does alpha-1-acid glycoprotein determine for infertility in polycystic ovary syndrome?

Basit Öğe Kaydı
dc.authorid0000-0003-3453-3852en_US
dc.authorid0000-0002-3394-2438en_US
dc.authorid0000-0002-3922-5915en_US
dc.contributor.authorDurmuş, Merve
dc.contributor.authorUzunlar, Özlem
dc.contributor.authorÇelik, Hümeyra
dc.contributor.authorÇandar, Tuba
dc.date.accessioned2023-08-14T13:39:53Z
dc.date.available2023-08-14T13:39:53Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: The underlying cause of metabolic abnormalities and ovarian dysfunction in PCOS is thought to chronic low-grade inflammation. This study aimed to show whether alpha-1-acid glycoprotein (AGP), an inflammatory marker, predicts the risk of infertility in fertile and infertile women with PCOS. Our study had a crossectional case-control design. Study design: A total of 20 fertile and 50 infertile patients with PCOS who wanted a child were in the early follicular phase were included in our study. Among the study groups (fertil (n = 20) and infertile (n = 50), AGP, CRP, NLR, BMI, FAI, VAI, triglyceride, HDL-cholesterol, fasting blood sugar, HOMA-IR, SHBG, testosterone values and waist circumference were measured. Results: Among the inflammatory markers compared in the fertile and infertile groups included in the study, only the difference between the AGP variable was statistically significant (p = 0.011). The mean AGP was found to higher at a statistically significant level in the infertile group (p < 0.05). Age, BMI, waist circumference and AGP were weakly positive and CRP was moderately positive in the infertile group (p < 0.05). Conclusion: AGP can be a good indicator of inflammation in PCOS, especially in infertility. Revealing the risk of infertility in PCOS with AGP measurement may contribute to the correct management of the reproductive process.en_US
dc.identifier.citationDurmuş, M., Uzunlar, Ö., Çelik, H., & Çandar, T. (2022). Does alpha-1-acid glycoprotein determine for infertility in polycystic ovary syndrome?. European Journal of Obstetrics & Gynecology and Reproductive Biology, 274, 155-159.en_US
dc.identifier.doi10.1016/j.ejogrb.2022.05.023
dc.identifier.endpage159en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.pmid35653904en_US
dc.identifier.startpage155en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.ejogrb.2022.05.023
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11517
dc.identifier.volume274en_US
dc.identifier.wosWOS:000807734200011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇelik, Hümeyra
dc.language.isoenen_US
dc.publisherElseiveren_US
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology and Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolycystic Ovary Syndromeen_US
dc.subjectAlpha-1-Acid Glycoproteinen_US
dc.subjectOrosomucoiden_US
dc.subjectGrade Chronic Inflammationen_US
dc.subjectAcute-Phase Proteinen_US
dc.subjectC-Reactive Proteinen_US
dc.titleDoes alpha-1-acid glycoprotein determine for infertility in polycystic ovary syndrome?en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
merve-durmus.pdf
Boyut:
423.83 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu