Prediction of lymph node metastasis in colon cancer via platelet to lymphocyte ratio and platelet count

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dc.authorid0000-0002-7475-7298
dc.authorid0000-0002-4067-251X
dc.authorid0000-0002-4326-2102
dc.contributor.authorÇatal, Oğuz
dc.contributor.authorÖzer, Bahri
dc.contributor.authorŞit, Mustafa
dc.date.accessioned2021-06-23T19:54:30Z
dc.date.available2021-06-23T19:54:30Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To investigate the value of preoperative blood tests in predicting lymph node metastasis in colon cancer patients undergoing surgery. Study Design: Obervational study. Place and Duration of Study: General Surgery Department, Bolu Abant Izzet Baysal University Medicine School, Turkey, between December 2012 and December 2018. Methodology: In 171 colon cancer patients, preoperative inflammatory markers such as albumin, C-reactive protein (CRP), platelet, neutrophil-to-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) counts were determined. Results: The present study albumin, CRP and NLR values were also not significantly different between the groups. PLR (p=0.008) and PLT (p=0.039) were significantly different between the lymph node groups. ROC analysis was performed for PLT and PLR for the prediction of lymph node metastasis (Group 2 and 3). Accuracy for PLT was 0.623 and accuracy for PLR was 0.65. A PLT value >321.5 was found to be 63.7% sensitive and 68.6% specific in predicting lymph node metastasis. A PLR value >155.81 was 70% sensitive and 41% specific for predicting lymph node metastasis. Conclusion: The platelet counts and PLR values are important in predicting lymph node metastasis in colon cancer, preoperatively. Platelet and PLR values may be more specific and sensitive in predicting preoperative lymph node metastasis in colon cancer patients.en_US
dc.identifier.endpage253en_US
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue3en_US
dc.identifier.pmid32169130en_US
dc.identifier.scopus2-s2.0-85081950985en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10560
dc.identifier.urihttps://www.jcpsp.pk/archive/2020/Mar2020/05.pdf
dc.identifier.volume30en_US
dc.identifier.wosWOS:000520024700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇatal, Oğuz
dc.institutionauthorÖzer, Bahri
dc.institutionauthorŞit, Mustafa
dc.language.isoenen_US
dc.publisherColl Physicians & Surgeons Pakistanen_US
dc.relation.ispartofJcpsp-Journal Of The College Of Physicians And Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColon Canceren_US
dc.subjectPlateleten_US
dc.subjectPlatelet to Lymphocyt Ratio (PLR)en_US
dc.subjectLymph Nodeen_US
dc.subjectMetastasisen_US
dc.subjectMarkers of Inflammationen_US
dc.titlePrediction of lymph node metastasis in colon cancer via platelet to lymphocyte ratio and platelet counten_US
dc.typeArticleen_US

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