Characteristics of the Turkish isolates of Francisella tularensis

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dc.authorid0000-0002-5052-481Xen_US
dc.authorid0000-0003-0502-432Xen_US
dc.authorid0000-0003-1514-1685en_US
dc.contributor.authorGürcan, Şaban
dc.contributor.authorKarabay, Oğuz
dc.contributor.authorKaradenizli, Aynur
dc.contributor.authorKaragöl, Çiğdem
dc.contributor.authorKantardjiev, Todor
dc.contributor.authorIvanov, Ivan N.
dc.date.accessioned2021-06-23T19:25:51Z
dc.date.available2021-06-23T19:25:51Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIn this study, cultures of patients with tularemia were evaluated, and antimicrobial susceptibilities of two Francisella tularensis strains were tested by disk diffusion and E-test methods. A high-resolution multiple-locus variable-number tandem repeat analysis (MLVA) comprising six variable-number tandem repeat loci was applied to elucidate the genetic relatedness among Turkish and Bulgarian isolates which were isolated in a recent outbreak. The patients were diagnosed in two outbreaks in two cities of Turkey in 2005 and 2006. A total of 16 samples from 12 patients were cultured, and PCR tests were carried out on 15 samples that were positive in five lymph node aspirates and two soft tissue aspirates. F. tularensis was isolated from the lymph nodes of two patients. Aminoglycosides, quinolones, chloramphenicole, tetracyclines, nitrofurantoin, and rifampicin inhibited growth of the isolates. The Turkish isolates appeared to share a common MLVA pattern with one of the four Bulgarian outbreak genotypes.en_US
dc.identifier.endpage225en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue3en_US
dc.identifier.pmid18503176en_US
dc.identifier.scopus2-s2.0-45849141296en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage223en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6284
dc.identifier.urihttps://www.niid.go.jp/niid/images/JJID/61/223.pdf
dc.identifier.volume61en_US
dc.identifier.wosWOS:000256389800014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKarabay, Oğuz
dc.language.isoenen_US
dc.publisherNational Instıtute Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal Of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFrancisella Tularensisen_US
dc.titleCharacteristics of the Turkish isolates of Francisella tularensisen_US
dc.typeArticleen_US

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