Salivary alpha-amylase levels in vertigo: can it be an autonomic dysfunction?

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dc.authorid0000-0002-4646-7250
dc.contributor.authorKorkmaz, Tanzer
dc.contributor.authorBiçer, Yusuf Özgür
dc.contributor.authorSerin, Erdinç
dc.contributor.authorSeyhan, Sinan
dc.contributor.authorŞanal, Serap Köybaşı
dc.date.accessioned2021-06-23T19:49:32Z
dc.date.available2021-06-23T19:49:32Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractWe aim to demonstrate possible autonomic dysfunction based on salivary alpha-amylase measurements during and after the vertigo attacks associated with Meniere disease (MD) and benign paroxysmal positional vertigo (BPPV). Patients admitted to the emergency room with a diagnosis of vertigo attacks caused by either MD (n = 15) or BPPV (n = 9) constituted the study groups. The control group (n = 10) consisted of volunteer patients admitted to the emergency department with minor soft-tissue trauma. The first saliva samples were obtained immediately during the attacks and the second and third samples were obtained on the third and fifteenth days of the attack, respectively. In the controls, the first sample was obtained after admission to the hospital and the second sample was obtained on the third day. Salivary alpha-amylase levels were evaluated. The difference between salivary alpha-amylase levels in patients with MD and BPPV was not significant. The amylase value measured early after the BPPV attack was significantly lower than that of the controls (p = 0.008). Although not significant, an undulating pattern of salivary alpha-amylase levels was observed with both diseases. An autonomic imbalance could be partly demonstrated by salivary alpha-amylase measurement early after the attack in patients with BPPV. Therefore, amylase may be a promising marker that is worth further investigation.en_US
dc.identifier.doi10.1177/014556131809700917
dc.identifier.endpage+en_US
dc.identifier.issn0145-5613
dc.identifier.issn1942-7522
dc.identifier.issue9en_US
dc.identifier.pmid30273427en_US
dc.identifier.scopus2-s2.0-85054087923en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage278en_US
dc.identifier.urihttps://doi.org/10.1177/014556131809700917
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9537
dc.identifier.volume97en_US
dc.identifier.wosWOS:000445971600006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBiçer, Yusuf Özgür
dc.institutionauthorSeyhan, Sinan
dc.institutionauthorŞanal, Serap Köybaşı
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofEnt-Ear Nose & Throat Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVertigoen_US
dc.subjectSalivary
dc.subjectAlpha-Amylase Level
dc.subjectDysfunction
dc.titleSalivary alpha-amylase levels in vertigo: can it be an autonomic dysfunction?en_US
dc.typeArticleen_US

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