Asymmetric dimethylarginine levels in allergic rhinitis and nasal polyposis

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dc.contributor.authorTosun, Mehmet
dc.contributor.authorApuhan, Tayfun
dc.date.accessioned2021-06-23T19:35:04Z
dc.date.available2021-06-23T19:35:04Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: Asymmetric dimethylarginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase. We aimed to investigate the ADMA levels in allergic rhinitis (AR) and nasal polyposis (NP). Materials and methods: A total of 29 AR patients, 21 NP patients, and 30 healthy subjects to be used as a control group were enrolled in the study. ADMA was measured in the AR, NP, and control groups with enzyme-linked immunosorbent assay. Any patients or control subjects with coronary artery disease, renal failure, diabetes mellitus, or hypertension were excluded from the study. Results: The mean ADMA serum concentration was 0.52 +/- 0.08 mu mol/L in the AR group, 0.62 +/- 0.10 mu mol/L in the NP group, and 0.67 +/- 0.09 mu mol/L in the control group. The ADMA serum concentration in the AR group was significantly lower than in the control group (P < 0.001). Considered together, the NP and AR groups had ADMA levels that were significantly lower than in the control group (P < 0.001). Conclusion: In the present study, lower ADMA levels were found in the AR and NP groups.en_US
dc.identifier.doi10.3906/sag-1204-111
dc.identifier.endpage458en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84878412744en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage455en_US
dc.identifier.trdizinid211677en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1204-111
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7702
dc.identifier.volume43en_US
dc.identifier.wosWOS:000321481200018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorTosun, Mehmet
dc.institutionauthorApuhan, Tayfun
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAsymmetric Dimethylarginineen_US
dc.subjectAllergic Rhinitisen_US
dc.subjectNasal Polyposisen_US
dc.titleAsymmetric dimethylarginine levels in allergic rhinitis and nasal polyposisen_US
dc.typeArticleen_US

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