Could red cell distribution width and mean platelet volume be a predictor for lumbar disc hernias?

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-1668-7850
dc.authorid0000-0002-0202-8555
dc.authorid0000-0001-7091-5650
dc.authorid0000-0003-2959-3092
dc.contributor.authorDağıstan, Yaşar
dc.contributor.authorDağıstan, Emine
dc.contributor.authorGezici, Ali Rıza
dc.contributor.authorHalıcıoğlu, Sıdıka
dc.contributor.authorAkar, Semih
dc.contributor.authorÖzkan, Nezih
dc.contributor.authorAktaş, Gülali
dc.date.accessioned2021-06-23T19:42:51Z
dc.date.available2021-06-23T19:42:51Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Lumbar disc herniation (LDH) causes major disabilities worldwide. Several studies in the literature had reported the correlation between radiculopathy and inflammatory markers. Mean platelet volume (MPV), red cell distribution width (RDW) and neutrophil to lymphocyte (N/L) ratio are parameters of hemogram which have been found to be associated with inflammatory conditions. Purpose - Since inflammation has an important role in lumbar disc hernias, and RDW, MPV and N/L ratio are also known to be in correlation with inflammation, we have investigated these parameters of the patients with lumbar disc hernias and compared them with the results of the healthy subjects. Methods - Our study group was composed of patients with lumbar disc hernia, whereas the control group was consisted of healthy volunteers whom visited our outpatient clinics for a routine check-up. Patient characteristics and hemogram parameters of the study cohort were obtained from computerized database system of our institution. SPSS software (SPSS 15.0 for Windows, Chicago, IL, USA) was used for the analysis. Results - There was no significant difference between study and control groups in terms of WBC, neutrophil count, lymphocyte count, neu\lym ratio, Hb, Htc, MCV, and PLT levels (all p>0.05). RDW was significantly increased in study group [15.6 (12.3-22.5)] when compared to control group [14.5(11.9-16.3)] (p=0.004). And MPV in the study group [9.25 (6.38-14.5)] was also significantly increased in comparison to the control subjects [8.8 (6-10.1)] (p=0.013). Discussion In this retrospective study, we found that, RDW and MPV values in hemograms were increased in patients with lumbar disc herniation when compared to the control group. Conclusions - We suggest that, elevated RDW and MPV may help physicians in decision taking to order radiological imagings in patients with symptoms which can be associated with possible LDH diagnosis. However, for the sake of precision, prospective studies with larger populations are needed.en_US
dc.identifier.doi10.18071/isz.69.0411
dc.identifier.endpage414en_US
dc.identifier.issn0019-1442
dc.identifier.issue11-12en_US
dc.identifier.pmid29733559en_US
dc.identifier.scopus2-s2.0-85009165605en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage411en_US
dc.identifier.urihttps://doi.org/10.18071/isz.69.0411
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8623
dc.identifier.volume69en_US
dc.identifier.wosWOS:000391162900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDağıstan, Yaşar
dc.institutionauthorDağıstan, Emine
dc.institutionauthorHalıcıoğlu, Sıdıka
dc.institutionauthorGezici, Ali Rıza
dc.institutionauthorAktaş, Gülali
dc.language.isoenen_US
dc.publisherLiteratura Medicaen_US
dc.relation.ispartofIdeggyogyaszati Szemle-Clinical Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectRed Cell Distribution Widthen_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.subjectInflammationen_US
dc.subjectLumbar Disc Herniaen_US
dc.titleCould red cell distribution width and mean platelet volume be a predictor for lumbar disc hernias?en_US
dc.typeArticleen_US

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