Association between hemogram parameters and coronary collateral development in subjects with non-ST-elevation myocardial infarction

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dc.authorid0000-0002-1495-1697en_US
dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-2399-9585en_US
dc.authorid0000-0003-3085-7964en_US
dc.authorid0000-0003-3817-851Xen_US
dc.contributor.authorSincer, İsa
dc.contributor.authorMansıroğlu, Aslı Kurtar
dc.contributor.authorAktaş, Gülali
dc.contributor.authorGüneş, Yılmaz
dc.contributor.authorKoçak, Mehmet Zahid
dc.date.accessioned2021-06-23T19:54:34Z
dc.date.available2021-06-23T19:54:34Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: Coronary collateral development (CCD) predicts the severity of coronary heart disease. Hemogram parameters, such as mean platelet volume (MPV), eosinophil, red cell distribution width, and platelet distribution width (PDW), are supposed novel inflammatory markers. We aimed to compare hemogram parameter values in patients presenting with non-ST-elevation myocardial infarction (NSTEMI) with adequate or inadequate CCD. METHODS: A total of 177 patients with NSTEMI undergoing coronary arteriography were enrolled and divided into two groups based on the development of CCD: one group with adequate CCD (n=88) and the other with impaired CCD (n=89). RESULTS: Baseline demographics and clinical risk factors were similar between the groups. Hemogram parameters were not significantly different between the two groups. However, compared to the inadequate CCD group, the median PDW was significantly higher in the adequate CCD group, 17.6 (1.4) vs. 17.8 (1.6) p=0.004. In a multivariate analysis, PDW (p=0.001, 95% CI for OR: 0.489(0,319-0,750) was found to be significantly different in the adequate CCD group compared to the inadequate CCD group. Pearson's correlation analysis revealed that PDW was significantly correlated with the Rentrop score (r=0.26, p<0.001). CONCLUSIONS: We suggest that since PDW is an index that is inexpensive and easy to assess, it could serve as a marker of CCD in patients with NSTEMI.en_US
dc.identifier.doi10.1590/1806-9282.66.2.160
dc.identifier.endpage165en_US
dc.identifier.issn1806-9282
dc.identifier.issue2en_US
dc.identifier.pmid32428150en_US
dc.identifier.scopus2-s2.0-85084964685en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage160en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.66.2.160
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10583
dc.identifier.volume66en_US
dc.identifier.wosWOS:000534475300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSincer, İsa
dc.institutionauthorAktaş, Gülali
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorGüneş, Yılmaz
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Collateral Developmenten_US
dc.subjectNon-ST-elevation Myocardial Infarctionen_US
dc.subjectHematological Parametersen_US
dc.subjectPlatelet Distributionen_US
dc.titleAssociation between hemogram parameters and coronary collateral development in subjects with non-ST-elevation myocardial infarctionen_US
dc.typeArticleen_US

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