The effects of levobupivacaine versus levobupivacaine plus magnesium infiltration on postoperative analgesia and laryngospasm in pediatric tonsillectomy patients

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dc.authorid0000-0001-5406-098Xen_US
dc.authorid0000-0003-0582-8723
dc.authorid0000-0002-0363-9307
dc.contributor.authorKaraaslan, Kazım
dc.contributor.authorYılmaz, Fahrettin
dc.contributor.authorGülcü, Nebahat
dc.contributor.authorSarpkaya, Ali
dc.contributor.authorÇolak, Cemil
dc.contributor.authorKoçoğlu, Hasan
dc.date.accessioned2021-06-23T19:25:51Z
dc.date.available2021-06-23T19:25:51Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The aim of this study was to evaluate whether the addition of magnesium to levobupivacaine wilt decrease the postoperative analgesic requirement or not, and to investigate the possible preventive effects on laryngospasm. Methods: Seventy-five children undergoing elective tonsillectomy and/or adenoidectomy surgery. The drug was prepared as only NaCl 0.9% for the first group (Group S, n = 25), Levobupivacaine 0.25% for the second group (Group L, n = 25), and levobupivacaine 0.25% plus magnesium sulphate 2 mg/kg for the third group (Group M, n = 25). Pain was recorded at 15th minute, 1st, 4th, 8th, 16th, and 24th hour postoperatively. Pain was evaluated using a modified Children's Hospital of Eastern Ontario pain scale (mCHEOPS). Incidence of postoperative nausea and vomiting (PONV) was assessed at various time intervals (0-2, 2-6, 6-24 h) by numeric rank score. Patients were followed for laryngospasm for 1 h in recovery room after extubation. Other complications appeared within 24 h postoperatively were recorded. Results: All postoperative CHEOPS values were tower than control in both groups. Analgesic requirement was decreased significantly in both groups in comparison with control patients, but this requirement was significantly tower in Group M (p < 0.05). Although laryngospasm was not observed in Group M, the difference between groups was not statistically significant. PONV was similar in both groups. Conclusions: Levobupivacaine and Levobupivacaine plus magnesium infiltration decrease the post-tonsillectomy analgesic requirement. Insignificant preventive effect of low doses of magnesium infiltration on laryngospasm observed in this study needs to be clarified by larger series. (C) 2008 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijporl.2008.01.029
dc.identifier.endpage681en_US
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.issue5en_US
dc.identifier.pmid18325601en_US
dc.identifier.scopus2-s2.0-41149166561en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage675en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2008.01.029
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6283
dc.identifier.volume72en_US
dc.identifier.wosWOS:000255321200021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaraaslan, Kazım
dc.institutionauthorYılmaz, Fahrettin
dc.institutionauthorGülcü, Nebahat
dc.institutionauthorSarpkaya, Ali
dc.institutionauthorKoçoğlu, Hasan
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPost-tonsillectomy Painen_US
dc.subjectLevobupivacaineen_US
dc.subjectMagnesiumen_US
dc.subjectLaryngospasmen_US
dc.subjectPONVen_US
dc.titleThe effects of levobupivacaine versus levobupivacaine plus magnesium infiltration on postoperative analgesia and laryngospasm in pediatric tonsillectomy patientsen_US
dc.typeArticleen_US

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