Could systemic inflammatory index predict diabetic kidney injury in type 2 diabetes mellitus?

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dc.authorid0000-0002-3836-2125en_US
dc.authorid0009-0007-0233-2403en_US
dc.authorid0000-0003-3651-4858en_US
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorÖzkul, Feyza Nihal
dc.contributor.authorBalcı, Sümeyye Buse
dc.date.accessioned2024-03-08T10:59:09Z
dc.date.available2024-03-08T10:59:09Z
dc.date.issued2023en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The systemic inflammatory index (SII) is a new inflammatory marker that has been the subject of various studies in diseases with chronic inflammation. Diabetic nephropathy is a disease associated with chronic inflammation. We aimed to evaluate the relationship between SII and diabetic nephropathy. Methods: Patients with diabetes who applied to our outpatient clinic were included in the study. Diabetic patients were divided into two groups: those with diabetic nephropathy and those without. In addition, healthy individuals who applied to our clinic for general check-ups during these dates were included as the control group. The SII values and other characteristics of the three study groups were compared. Results: The median SII value for those with DKI was 584 (178-4819); for those without DKI, it was 282 (64-618); and for the control group, it was 236 (77.5-617) (p < 0.001). SII was significantly and positively correlated with BMI, weight, blood glucose, HbA1c, CRP, and creatinine, and negatively correlated with the glomerular filtration rate (GFR) value. SII values higher than 336 have 75% sensitivity and 70% specificity in detecting DKI. Conclusion: The SII value can predict diabetic kidney injury in diabetics, and it can be used as an adjunctive diagnostic tool.en_US
dc.identifier.citationTaslamacioglu Duman, T., Ozkul, F. N., & Balci, B. (2023). Could Systemic Inflammatory Index Predict Diabetic Kidney Injury in Type 2 Diabetes Mellitus?. Diagnostics, 13(12), 2063.en_US
dc.identifier.doi10.3390/diagnostics13122063
dc.identifier.endpage12en_US
dc.identifier.issn2075-4418
dc.identifier.issue12en_US
dc.identifier.pmid37370958en_US
dc.identifier.scopus2-s2.0-85163983324en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://dx.doi.org/10.3390/diagnostics13122063
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12071
dc.identifier.volume13en_US
dc.identifier.wosWOS:001014202800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorÖzkul, Feyza Nihal
dc.institutionauthorBalcı, Sümeyye Buse
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofDiagnosticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetic Kidney Injuryen_US
dc.subjectInflammationen_US
dc.subjectSystemic Inflammatory Indexen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.subjectBlood Mononuclear-Cellsen_US
dc.titleCould systemic inflammatory index predict diabetic kidney injury in type 2 diabetes mellitus?en_US
dc.typeArticleen_US

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