Frequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO)

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dc.authorid0000-0002-6049-7229en_US
dc.authorid0000-0003-3097-4896en_US
dc.authorid0000-0002-1072-0592en_US
dc.authorid0000-0001-8725-3323en_US
dc.authorid0000-0001-5842-7849en_US
dc.contributor.authorTanrıverdi, Elif
dc.contributor.authorTutar, Nuri
dc.contributor.authorŞentürk, Ayşegül
dc.contributor.authorBahadır, Ayşe
dc.contributor.authorAksel, Nimet
dc.contributor.authorÖzsarı, Emine
dc.date.accessioned2023-09-15T12:59:05Z
dc.date.available2023-09-15T12:59:05Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and beneficial in terms of bleeding; however, studies that present up-to-date life data are necessary. Aims: To evaluate the frequency of using DOACs, which are prescribed with a limited number of indications in our country, and real-life data results. Study Design: Cross-sectional study Methods: This cross-sectional survey collected the clinical data (history, current treatment, treatment duration, etc.) of patients with pulmonary thromboembolism and who applied to the physician for follow-up between October 15, 2019, and March 15, 2020. The researchers kept the patient records sequentially. Results: Data from 836 patients with acute pulmonary thromboembolism from 25 centers were collected, and DOAC was used in 320 (38.5%) of them. The most preferred DOAC was rivaroxaban (n = 294, 91.9%). DOAC was mostly preferred because it could not provide an effective INR level with warfarin (n=133, 41.6%). Bleeding was observed in 13 (4%) patients. Conclusion: The use of direct oral anticoagulants is becoming almost as widespread as conventional therapy. Real-life data results are important for their contribution to clinical practice.en_US
dc.identifier.citationTanrıverdi, E., Tutar, N., Şentürk, A., Bahadır, A., Aksel, N., Yetkin, N. A., ... & Salık, B. (2022). Frequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO). Balkan Medical Journal, 39(2), 148.en_US
dc.identifier.doi10.4274/balkanmedj.galenos.2021.2021-10-19
dc.identifier.endpage152en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue2en_US
dc.identifier.pmid35330566en_US
dc.identifier.scopus2-s2.0-85127062858en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage148en_US
dc.identifier.trdizinid1133635en_US
dc.identifier.urihttp://dx.doi.org/10.4274/balkanmedj.galenos.2021.2021-10-19
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11709
dc.identifier.volume39en_US
dc.identifier.wosWOS:000779560300009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzsarı, Emine
dc.language.isoenen_US
dc.publisherGalenos Publishing Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVenous Thromboembolismen_US
dc.subjectRivaroxabanen_US
dc.subjectWarfarinen_US
dc.subjectDabigatranen_US
dc.subjectManagementen_US
dc.titleFrequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO)en_US
dc.typeArticleen_US

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