Association between novel inflammatory markers derived from hemogram indices and metabolic parameters in type 2 diabetic men

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-2811-0052en_US
dc.authorid0000-0003-3085-7964en_US
dc.authorid0000-0003-4201-9757
dc.authorid0000-0002-4162-5563
dc.authorid0000-0002-7422-1442
dc.contributor.authorBilgin, Satılmış
dc.contributor.authorAktaş, Gülali
dc.contributor.authorKoçak, M. Zahid
dc.contributor.authorAtak, Burçin M.
dc.contributor.authorKurtkulağı, Özge
dc.contributor.authorDuman, Tuba T.
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:17:13Z
dc.date.available2021-06-23T19:17:13Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: Hemogram indices were proposed as novel inflammatory markers in chronic conditions and inflammation has substantial role in the pathogenesis of type 2 diabetes mellitus (T2DM). We aimed to observe hemogram parameters of type 2 diabetic male subjects with various age groups in well and poorly controlled subsets. Methods: Data of type 2 diabetic men enrolled to the study were recorded from patient files of the institution. Study population were grouped into three according to the age. Group A was consisted of patients younger than 55 years, Group B was consisted of patients aged between 55 and 64 years, and Group C was consisted of patients aged 65 years or older. Data of the study groups were compared. Results: Study population was consisted of 130 subjects; 44 in Group A and 43 in each of Groups B and C. Median red cell distribution width (RDW) (p = .04), mean RDW to platelet ratio (RPR) (p = .006), median mean platelet volume to platelet ratio (MPR) (p = .02) levels of the study groups were statistically different. HbA1c level was significantly and positively correlated with RDW (r = 0.45, p < .001), neutrophil to lymphocyte ratio (NLR) (r = 0.47, p < .001), mean platelet volume to lymphocyte ratio (MLR) (r = 0.35, p < .001), MPR (r = 0.26, p = .003), and RPR (r = 0.37, p < .001) levels. Conclusion: Elevated RDW, NLR, MLR, MPR, and RPR levels in diabetic men should trigger the measurement of HbA1c since each were strongly correlated with HbA1c level. Moreover, elevated RDW, NLR, MLR, and RPR could be marker of worse diabetic control in men with T2DM.en_US
dc.identifier.doi10.1080/13685538.2019.1632283
dc.identifier.endpage927
dc.identifier.issn1368-5538
dc.identifier.issue5
dc.identifier.pmid31250688en_US
dc.identifier.scopus2-s2.0-85068225719en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage923
dc.identifier.urihttps://doi.org/10.1080/13685538.2019.1632283
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5290
dc.identifier.volume23
dc.identifier.wosWOS:000473818700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBilgin, Satılmış
dc.institutionauthorAktaş, Gülali
dc.institutionauthorKoçak, M. Zahid
dc.institutionauthorAtak, Burçin M.
dc.institutionauthorKurtkulağı, Özge
dc.institutionauthorDuman, Tuba T.
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofAging Maleen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInflammationen_US
dc.subjectType 2 Diabetes Mellitusen_US
dc.subjectHemogram Indicesen_US
dc.titleAssociation between novel inflammatory markers derived from hemogram indices and metabolic parameters in type 2 diabetic menen_US
dc.typeArticleen_US

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