Cerebrospinal fluid levels of interleukin-17 and interleukin-34 in patients with neuro-behcet’s syndrome

Basit Öğe Kaydı
dc.authorid0000-0002-9026-4485
dc.authorid0000-0001-5524-5767
dc.authorid0000-0001-8616-832X
dc.authorid0000-0002-9647-4432
dc.contributor.authorÖgün, Muhammed Nur
dc.contributor.authorKarabörk, Şeyda
dc.contributor.authorÖnerli, Merve
dc.contributor.authorTürkoğlu, Şule Aydın
dc.contributor.authorYıldız, Serpil
dc.date.accessioned2021-06-23T19:52:05Z
dc.date.available2021-06-23T19:52:05Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBehcet's disease (BD) is a rather rare chronic multisystemic vasculitic disease. Clear neurological involvement is observed in up to 49% of patients with BD. Cytokines play a pivotal role in the pathogenesis of BD. Data on the cerebrospinal fluid (CSF) levels of cytokines in patients with Neuro-Behcet's disease (NBD) are limited. We measured the CSF levels of Interleukin (IL)-17A, IL-17F, and IL-34 in 7 patients with NBD (median age of 38 years). Eleven control subjects were of a median age of 42 years. There was no significant difference in the male-to-female ratio and age between the NBD and control groups (P > 0.05). There was also no significant difference in biochemical values of CSF between NBD patients and control subjects. The CSF levels of IL-17 was significantly higher in patients with active NBD compared to the control (P < 0.05), whereas the CSF levels of IL-34 showed no difference compared to the control group (P > 0.05). This is the first study investigating the CSF levels of IL-34 in patients with NBD. Further studies with a larger sample size are required to confirm the role and values of the IL-34 levels in NBD.en_US
dc.identifier.doi10.1007/s11062-019-09797-6
dc.identifier.endpage87en_US
dc.identifier.issn0090-2977
dc.identifier.issn1573-9007
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85069965650en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.1007/s11062-019-09797-6
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10094
dc.identifier.volume51en_US
dc.identifier.wosWOS:000480739800005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKarabörk, Şeyda
dc.institutionauthorÖgün, Muhammed Nur
dc.institutionauthorÖnerli, Merve
dc.institutionauthorTürkoğlu, Şule Aydın
dc.institutionauthorYıldız, Serpil
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofNeurophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeuro-Behcet's Syndromeen_US
dc.subjectCerebrospinal Fluiden_US
dc.subjectCytokinesen_US
dc.subjectInterleukinsen_US
dc.subjectIL-17en_US
dc.subjectIL-34en_US
dc.titleCerebrospinal fluid levels of interleukin-17 and interleukin-34 in patients with neuro-behcet’s syndromeen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
m-n-ogun.pdf
Boyut:
760.1 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu