XEN gel implant versus gonioscopy-assisted transluminal trabeculotomy for the treatment of open-angle glaucoma

dc.authorid0000-0001-9945-793Xen_US
dc.contributor.authorOlgun, Ali
dc.contributor.authorAktaş, Zeynep
dc.contributor.authorÜçgül, Ahmet Yücel
dc.date.accessioned2021-06-23T19:54:17Z
dc.date.available2021-06-23T19:54:17Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives To compare successes and complications of XEN GEL Stent implantation and gonioscopy-assisted transluminal trabeculotomy (GATT) surgery in patients with open-angle glaucoma (OAG). Methods The multicentre, non-randomized, comparative, interventional, retrospective chart review study included 114 eyes undergoing XEN implantation and 107 eyes undergoing GATT for treatment of OAG. A comprehensive ophthalmic examination consisting of best-corrected LogMAR visual acuity (BCVA), Goldmann Applanation Tonometry, biomicroscopy, fundoscopy and gonioscopy was performed, and then, clinical findings, complications and number of antiglaucomatous medications were noted at the 3-, 6-, 12-, 18- and 24-month postoperative visits. Surgical success was defined as IOP <= 21 mmHg and 20% >= IOP reduction from baseline with (qualified success) or without (complete success) further medication, and without any further IOP-lowering surgery. Results The mean ages were 65.8 +/- 10.6 and 59.1 +/- 14.3 in XEN and GATT groups, respectively (p = 0.001). In XEN group, the percentage of IOP reduction and need of medication were significantly more improved than those in GATT group. The complete surgical success rates were 34.2% and 50.5% in XEN and GATT groups, respectively (p = 0.039), with a success rate of 41.1% in total. Qualified surgical success rates were 97.4% and 89.7% in XEN and GATT groups, respectively (p = 0.025), with a success rate of 93.7% in total. Transient hyphema, the most observed postoperative complication in both groups, cleared in a few days. Conclusions Both MIGS have good efficacy and safety outcomes in lowering IOP and need of medication in patients with OAG. XEN Gel Stent implantation may be preferred in patients with lower IOP values targeted.en_US
dc.identifier.doi10.1007/s10792-019-01271-w
dc.identifier.endpage1093en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue5en_US
dc.identifier.pmid31907697en_US
dc.identifier.scopus2-s2.0-85077628252en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1085en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-019-01271-w
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10487
dc.identifier.volume40en_US
dc.identifier.wosWOS:000529689200005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÜçgül, Ahmet Yücel
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlaucomaen_US
dc.subjectGonioscopyen_US
dc.subjectIntraocular Pressureen_US
dc.subjectStenten_US
dc.subjectTrabeculotomyen_US
dc.subjectXENen_US
dc.titleXEN gel implant versus gonioscopy-assisted transluminal trabeculotomy for the treatment of open-angle glaucomaen_US
dc.typeArticleen_US

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