Antibacterial efficacy of copper-added chitosan nanoparticles: A confocal laser scanning microscopy analysis
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Abstract
The aim of this study was to evaluate the antibacterial efcacy of copper added chitosan nanoparticles (CU-CNPs) as an
irrigation solution with diferent irrigants in terms of eliminating Enterococcus Faecalis (E. faecalis) from the root canals.
Fifty mandibular premolar teeth were prepared and infected with E. faecalis for 21 days. After the incubation period, samples
were randomly divided into a control group irrigated with distilled water and 4 experimental groups (n=10) irrigated with
as follows, %6 NaOCl, %6 NaOCl+%9 editronate (HEBP), Chitosan nanoparticles (CNPs), and CU-CNPs. To calculate the
proportion of dead E. faecalis cell volume, stained using LIVE/DEAD BacLight Bacterial Viability Kit and were scanned
using confocal laser scanning microscope (CLSM). All the irrigation solutions signifcantly (P<.05) killed the bacteria in
the canal, except for the control group. CU-CNPs solution killed the highest (P<.05) number of bacteria compared with
the other experimental groups. No signifcant diference was found between CNPs, NaOCl+HEBP, and NaOCl in terms of
antibacterial activity. CU-CNPs solution was exhibited higher antibacterial efcacy against E. faecalis.
Açıklama
Anahtar Kelimeler
Chitosan Nanoparticules, Enterococcus Faecalis, Irrigation, Root Canal Disinfection, Sodium Hypochlorite
Kaynak
Odontology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
109
Sayı
4
Künye
Keskin, N. B., Aydın, Z. U., Uslu, G., Özyürek, T., Erdönmez, D., & Gündoğar, M. (2021). Antibacterial efficacy of copper-added chitosan nanoparticles: A confocal laser scanning microscopy analysis. Odontology, 109(4), 868-873.
