Gamma-glutamyl-transferase may predict COVID-19 outcomes in hospitalised patients

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dc.authorid0000-0003-3858-0103en_US
dc.authorid0000-0002-4414-9929en_US
dc.authorid0000-0002-7477-6640en_US
dc.authorid0000-0002-6054-9244en_US
dc.authorid0000-0002-3896-0934en_US
dc.contributor.authorKasapoğlu, Benan
dc.contributor.authorYozgat, Ahmet
dc.contributor.authorTanoğlu, Alpaslan
dc.contributor.authorCan, Güray
dc.contributor.authorSakin, Yusuf Serdar
dc.date.accessioned2023-07-19T11:50:24Z
dc.date.available2023-07-19T11:50:24Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim In this study, we aimed to define the predictive role of liver function tests at admission to the hospital in outcomes of hospitalised patients with COVID-19. Material and Method In this multicentric retrospective study, a total of 269 adult patients (>= 18 years of age) with confirmed COVID-19 who were hospitalised for the treatment were enrolled. Demographic features, complete medical history and laboratory findings of the study participants at admission were obtained from the medical records. Patients were grouped regarding their intensive care unit (ICU) requirements during their hospitalisation periods. Results Among all 269 participants, 106 were hospitalised in the ICU and 66 died. The patients hospitalised in ICU were older than patients hospitalised in wards (P = .001) and expired patients were older than alive patients (P = .001). Age, elevated serum D-dimer, creatinine and gamma-glutamyl transferase (GGT) levels at admission were independent factors predicting ICU hospitalisation and mortality in COVID-19 patients. Conclusion In conclusion, in hospitalised patients with COVID-19, laboratory data on admission, including serum, creatinine, GGT and d-dimer levels have an important predictive role for the ICU requirement and mortality. Since these tests are readily available in all hospitals and inexpensive, some predictive formulas may be calculated with these parameters at admission, to define the patients requiring intensive care.en_US
dc.identifier.citationKasapoglu, B., Yozgat, A., Tanoglu, A., Can, G., Sakin, Y. S., & Kekilli, M. (2021). Gamma‐glutamyl‐transferase may predict COVID‐19 outcomes in hospitalised patients. International Journal of Clinical Practice, 75(12), e14933.en_US
dc.identifier.doi10.1111/ijcp.14933
dc.identifier.endpage6en_US
dc.identifier.issue12en_US
dc.identifier.pmid34605109en_US
dc.identifier.scopus2-s2.0-85116599228en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://dx.doi.org/10.1111/ijcp.14933
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11314
dc.identifier.volume75en_US
dc.identifier.wosWOS:000705547700001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorCan, Güray
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiver Function Tests (LFTsen_US
dc.subjectAngiotensin-Converting Enzyme 2 (ACE2en_US
dc.subjectLDHen_US
dc.titleGamma-glutamyl-transferase may predict COVID-19 outcomes in hospitalised patientsen_US
dc.typeArticleen_US

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