The etiology and clinical features of anaphylaxis in a developing country: a nationwide survey in Turkey

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dc.authorid0000-0002-8183-0190en_US
dc.authorid0000-0002-1780-4801
dc.contributor.authorCivelek, Ersoy
dc.contributor.authorErkoçoğlu, Mustafa
dc.contributor.authorAkan, Ayşegül
dc.contributor.authorÖzcan, Celal
dc.contributor.authorKaya, Ayşenur
dc.contributor.authorTokaç, Mahmut
dc.date.accessioned2021-06-23T19:44:59Z
dc.date.available2021-06-23T19:44:59Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Despite the increasing frequency of anaphylaxis, there is inadequate information on the etiology and clinical features in various countries, regions and age groups, especially in developing countries. Objective: Our aim is to assess the etiology and clinical findings of anaphylaxis in Turkey. Gathering reliable data about the etiology and clinical findings of anaphylaxis in the general population will decrease the related morbidity and mortality. Method: We obtained the names and phone numbers of individuals who had been prescribed an epinephrine auto-injector with a diagnosis of anaphylaxis from ministry of health. Demographic data, clinical history of the first episode of anaphylaxis including the triggering agent, clinical findings, course of hospitalization, and the management of anaphylaxis were obtained by phone survey. Results: A total of 843 patients with a mean age of 21.4 +/- 17.3 years were evaluated. There was a significant male predominance among children younger than 10 years of age but a female predominance in older subjects. The most common causes of anaphylaxis were foods(40.1%) in children and bee venom(60.8%) in adults. The biphasic reaction rate was 4.3% and the median length of stay at an emergency department was 4.0 hours. Almost 60% of the patients had recurrent anaphylaxis episodes. Only 10.7% of the cases were prescribed an epinephrine auto-injector at their first anaphylaxis episode and only 59.2% of the patients were referred to an allergist during discharge from the emergency department. Conclusions: In Turkey, bee venom was the most common cause of anaphylaxis, followed by food and drug. While more than a half of patients reported recurrent attacks; only 10% had been prescribed epinephrine auto-injector kit after their first episode. Strategies to improve the anaphyalxis management are therefore urgently required.en_US
dc.identifier.doi10.12932/AP0752
dc.identifier.endpage219en_US
dc.identifier.issn0125-877X
dc.identifier.issn2228-8694
dc.identifier.issue4en_US
dc.identifier.pmid27543730en_US
dc.identifier.scopus2-s2.0-85028981528en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage212en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9080
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000429950700006
dc.identifier.volume35en_US
dc.identifier.wosWOS:000429950700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorErkoçoğlu, Mustafa
dc.institutionauthorTokaç, Mahmut
dc.language.isoenen_US
dc.publisherAllergy Immunol Soc Thailand,en_US
dc.relation.ispartofAsian Pacific Journal Of Allergy And Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnaphylaxisen_US
dc.subjectEpidemiologyen_US
dc.subjectEtiologyen_US
dc.subjectEpinephrine Autoinjectoren_US
dc.subjectFood Allergyen_US
dc.subjectVenom Allergyen_US
dc.subjectDrug Allergyen_US
dc.titleThe etiology and clinical features of anaphylaxis in a developing country: a nationwide survey in Turkeyen_US
dc.typeArticleen_US

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