Images in emergency medicine: acute severe coronary spasm associated with 5-fluorouracil chemotherapy

Cardiotoxicity is an uncommon adverse effect of 5-FU treatment. Prevalence of 5- fluorouracil (FU) - induced cardiotoxicity is 2–18%, and represents an interesting clinical challenge.1 A 62 year old male was admitted to our emergency department with severe dyspnea, chest pain, diaphoresis, nausea, and pruritis after the completition of a regimen of 5-FU chemotherapy for gastric adenocarcinoma.