C-reactive protein-to-lymphocyte ratio is a reliable marker in patients with COVID-19 infection: the CLEAR COVID study

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dc.authorid0000-0001-6262-6103en_US
dc.authorid0000-0003-2811-0052en_US
dc.authorid0000-0002-4162-5563en_US
dc.authorid0000-0002-3836-2125en_US
dc.authorid0000-0001-7306-5233en_US
dc.contributor.authorDemirkol, Muhammed Emin
dc.contributor.authorBilgin, Satılmış
dc.contributor.authorKahveci, Gizem
dc.contributor.authorKurtkulağı, Özge
dc.contributor.authorTel, Burçin Meryem Atak
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorAktaş, Gülali
dc.date.accessioned2024-03-14T09:33:05Z
dc.date.available2024-03-14T09:33:05Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: COVID-19 infection is characterized with elevation of inflammatory markers in bloodstream. A novel inflammatory marker, C-reactive protein (CRP)-to-lymphocyte ratio (CLR), is suggested to be associated with inflammation. We aimed to compare the CLR values of the deceased COVID-19 patients to the CLR of survived subjects. Materials and Methods: The patients with COVID-19 whom presented to outpatient or inpatient clinics of AbantIzzet Baysal University Hospital were enrolled to the present retrospective study. Subjects were grouped as either deceased or survived. CLR values of the groups were compared. Results: Study cohort was consisted of 568 subjects in deceased and 4753 patients in survived group. Median CLR of the deceased and survived groups were 90 (0.2-1679)% and 11 (0.2-1062)%, respectively (p < 0.001). The sensitivity (75%) and specificity (70%) of CLR (> 23.4% level) in detecting mortality were higher than those of CRP and ferritin (AUC: 0.80, p < 0.001, 95% CI: 0.78-0.82). Conclusion: We suggest that elevated CLR levels in COVID-19 patients on admission should alert physicians for poor outcome.en_US
dc.identifier.citationDemirkol, M. E., Bilgin, S., Kahveci, G., Kurtkulagi, O., Atak Tel, B. M., Duman, T. T., & Aktas, G. (2022). C-reactive protein-to-lymphocyte ratio is a reliable marker in patients with COVID-19 infection: the CLEAR COVID study. Cirugía y cirujanos, 90(5), 596-601.en_US
dc.identifier.doi10.24875/CIRU.22000124
dc.identifier.endpage601en_US
dc.identifier.issn0009-7411
dc.identifier.issue5en_US
dc.identifier.pmid36327470en_US
dc.identifier.scopus2-s2.0-85141235738en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage596en_US
dc.identifier.urihttp://dx.doi.org/10.24875/CIRU.22000124
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12087
dc.identifier.volume90en_US
dc.identifier.wosWOS:000913104100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDemirkol, Muhammed Emin
dc.institutionauthorBilgin, Satılmış
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorAktaş, Gülali
dc.language.isoenen_US
dc.publisherMexican Acad Surgeryen_US
dc.relation.ispartofCirugia Y Cirujanosen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectMortalityen_US
dc.subjectInflammationen_US
dc.subjectC-reactive Protein-to-lymphocyte Ratioen_US
dc.subjectClinical-Significanceen_US
dc.subjectSars-Cov-2en_US
dc.titleC-reactive protein-to-lymphocyte ratio is a reliable marker in patients with COVID-19 infection: the CLEAR COVID studyen_US
dc.title.alternativeLa proporción de proteína C reactiva a linfocitoE es un marcador confiable en pacientes con infección por COVID-19; el estudio CLEAR COVIDen_US
dc.typeArticleen_US

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