Serum cortistatin levels in patients with ocular active and ocular inactive Behcet Disease

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dc.authorid0000-0003-4468-3985en_US
dc.contributor.authorBalbaba, Mehmet
dc.contributor.authorUlaş, Fatih
dc.contributor.authorPostacı, Sevinç Arzu
dc.contributor.authorÖz, Burak
dc.contributor.authorAydın, Süleyman
dc.date.accessioned2021-06-23T19:55:02Z
dc.date.available2021-06-23T19:55:02Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: To evaluate serum cortistatin (CST) levels in patients with ocular active and ocular inactive Behcet disease (BD) and its relationship with disease activity. Methods: 24 BD patients with ocular active, 24 BD patients with ocular inactive patients and 24 healthy control subjects were included in the study. Results: In ocular active and ocular inactive BD patients and healthy control subjects, the mean serum CST levels were 4.38 +/- 1.63ng/ml, 5.46 +/- 1.81ng/ml and 7.56 +/- 1.73ng/ml, respectively. ESR, serum CRP, CST levels and NLR were significantly different between the groups (p < 0.001 for all). The CST levels were similar between ocular active and inactive BD patient groups (p = 0.197). ESR, CRP and NLR were significantly higher in ocular active BD patients compared to ocular inactive BD patients and healthy control subjects (p < 0.05 for all). Conclusion: Serum CST level was significantly lower in BD patients. CST may be a neuropeptide that plays a role in the pathogenesis of BD.en_US
dc.identifier.doi10.1080/09273948.2019.1610461
dc.identifier.endpage605en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue4en_US
dc.identifier.pmid31314641en_US
dc.identifier.scopus2-s2.0-85070287873en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage601en_US
dc.identifier.urihttps://doi.org/10.1080/09273948.2019.1610461
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10711
dc.identifier.volume28en_US
dc.identifier.wosWOS:000476125200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology And Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet Diseaseen_US
dc.subjectBehcet Disease Ocular Attack Score 24en_US
dc.subjectCortistatinen_US
dc.subjectC-reactive Proteinen_US
dc.subjectErythrocyte Sedimentation Rateen_US
dc.subjectNeutrophil-lymphocyte Ratioen_US
dc.titleSerum cortistatin levels in patients with ocular active and ocular inactive Behcet Diseaseen_US
dc.typeArticleen_US

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