Investigation of the effects of aloe barbadensis on rat ovaries: A preliminary study

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dc.authorid0000-0002-0334-1658
dc.contributor.authorKosif, Rengin
dc.contributor.authorAktaş, R. Gülhan
dc.date.accessioned2021-06-23T19:26:03Z
dc.date.available2021-06-23T19:26:03Z
dc.date.issued2009
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractEffects of Aloe barbadensis, a type of Aloe vera, on ovaries were investigated during pregnancy. A. vera gel, a commercial and nontherapeutic form of A. barbadensis, was used for this purpose. Three groups (one control and two test groups) of female Wistar albino rats with no prior births were studied. Group I was administered 25 mg (140 mg/kg) of A. barbadensis/day both orally and through gavage. A. barbadensis was contained in capsules with 500 mg of soybean oil; therefore Group II was administered 500 mg of soybean oil. Group III was the control group. All three groups were given normal food and water ad libitum. The substance had been administered for 20 days until birth. Ovaries were examined histologically. Vascular increase and the hyperemic form of ovary in the group administered A. barbadensis were notable. Decrease in primary follicle numbers, increase in secondary follicle numbers, and diminishment of secondary follicle diameters occurred in ovaries. The histological changes imply an angiogenesis effect of A. barbadensis and an effect like that of follicle-stimulating hormone in ovaries.en_US
dc.identifier.doi10.1089/jmf.2009.0035
dc.identifier.endpage1397en_US
dc.identifier.issn1096-620X
dc.identifier.issn1557-7600
dc.identifier.issue6en_US
dc.identifier.pmid20041799en_US
dc.identifier.scopus2-s2.0-74349089442en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1393en_US
dc.identifier.urihttps://doi.org/10.1089/jmf.2009.0035
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6392
dc.identifier.volume12en_US
dc.identifier.wosWOS:000273180900032en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKosif, Rengin
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofJournal Of Medicinal Fooden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAloe Barbadensisen_US
dc.subjectMorphologyen_US
dc.subjectRat Ovaryen_US
dc.titleInvestigation of the effects of aloe barbadensis on rat ovaries: A preliminary studyen_US
dc.typeArticleen_US

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