Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment?

dc.contributor.authorUzun, Tuğçenur
dc.contributor.authorToptaş, Orçun
dc.date.accessioned2021-06-23T19:54:12Z
dc.date.available2021-06-23T19:54:12Z
dc.date.issued2020
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Ağız Diş ve Çene Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractSARS (Severe Acute Respiratory Syndrome Coronavirus)-CV-2 (2019-nCov), which showed up in China in December 2019 and spread all over the world, has becomed a serious health problem. An effective, safe and proven treatment has not yet been found. Chloroquine has been recommended by some authors to be used for the treatment of patients infected with this virus however chloroquine may have side effects and drug resistance problems. Artesunate is a semisynthetic derivative of artemisinin, an antimalarial drug. Artesunate was thought to be an effective treatment for covid-19 because of its anti-inflammatory activity, NF-kappa B (nuclear Factor kappa B)-coronavirus effect and chloroquine-like endocytosis inhibition mechanism.en_US
dc.identifier.doi10.1186/s13020-020-00336-8
dc.identifier.issn1749-8546
dc.identifier.issue1en_US
dc.identifier.pmid32514287en_US
dc.identifier.scopus2-s2.0-85085658326en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s13020-020-00336-8
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10460
dc.identifier.volume15en_US
dc.identifier.wosWOS:000538827800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorToptaş, Orçun
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofChinese Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSARS-CoV-2en_US
dc.subjectChoroquineen_US
dc.subjectArtesunateen_US
dc.titleArtesunate: could be an alternative drug to chloroquine in COVID-19 treatment?en_US
dc.typeArticleen_US

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