Nitrite/Nitrate and malondialdehyde levels in nasal polyp

Basit Öğe Kaydı
dc.authorid0000-0002-4060-3354
dc.contributor.authorBuğdaycı, Güler
dc.contributor.authorKaymakçı, M.
dc.date.accessioned2021-06-23T19:25:57Z
dc.date.available2021-06-23T19:25:57Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this study was to examine the pathophysiological role of NO (nitric oxide) and MDA (malondialdehyde) in tissue in patients with nasal polyposis. We measured nitrite/nitrate (Nitrite/Nitrate; NO(2)(-)/NO(3)(-)) and MDA in tissue and plasma of NP patients (n=20) and controls (n=20). MDA level expressed as the concentration of substances reacting to thiobarbituric acid and production of NO (concentration of nitrite/nitrate in plasma) by the Griess reaction were determined. The level of NO(2)(-) and NO(3)(-) in tissue are higher than that of the normal tissue (p<0.05). The level of MDA in tissue are higher than that of the normal tissue (p<0.05). The level of NO(2)(-) and NO(3)(-) in plasma of two groups are similar (p>0.05). The level of MDA in plasma is higher than that in the normal controls (p<0.05). The change in NO(2)(-)/NO(3)(-) and MDA levels of nasal polyp patients was demonstrated. Further studies are required concerning the significance of changes in lipid peroxidation and nitrite levels in pathogenesis of nasal polyp.en_US
dc.identifier.doi10.1170/119
dc.identifier.endpage1045en_US
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1043en_US
dc.identifier.urihttps://www.cellmolbiol.org/index.php/CMB/article/view/1026/370
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6343
dc.identifier.volume54en_US
dc.identifier.wosWOS:000267199700003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBuğdaycı, Güler
dc.language.isoenen_US
dc.publisherCMB Associationen_US
dc.relation.ispartofCellular And Molecular Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInflammationen_US
dc.subjectOxidative Stressen_US
dc.subjectMalondialdehydeen_US
dc.subjectNitric Oxideen_US
dc.subjectNasal Polyposisen_US
dc.titleNitrite/Nitrate and malondialdehyde levels in nasal polypen_US
dc.typeArticleen_US

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