Could thrombocyte parameters be an inflammatory marker in the brucellosis?

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dc.authorid0000-0001-7306-5233
dc.authorid0000-0002-5643-3038
dc.authorid0000-0002-3156-1076
dc.authorid0000-0001-6133-9604
dc.authorid0000-0002-2860-1794
dc.contributor.authorKüçükbayrak, Abdülkadir
dc.contributor.authorTaş,Tekin
dc.contributor.authorTosun, Mehmet
dc.contributor.authorAktaş, Gülali
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorHakyemez, İsmail Necati
dc.contributor.authorKoçoğlu, Esra
dc.date.accessioned2021-06-23T18:56:03Z
dc.date.available2021-06-23T18:56:03Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim To investigate links between platelet parameters mean platelet volume (MPV), platelet count (PC), platelet distribution width (PDW), platelet mass (PM) and brucella tube agglutination titers (BSTAT) in patients with brucellosis. Initially, PC, MPV, PM and PDW calculations were compared between periods before and after treatment. The correlation between inlammation markers (erythrocyte sedimentation rate, ESR, white blood cell count, WBC, and C reactive protein, CRP) and platelet parameters was subsequently investigated. Methods This self-controlled study included 40 patients who had positive BSTAT at least at a titer of 1/160. Platelet parameters and inlammation values (CRP, ESR) at the time of positive BSTAT at least at a titer of 1/160 (pre-treatment) were compared with control of the same parameters at the time when BSTAT became negative or when the titers reduced 4 folds (post-treatment). Results Mean platelet volume values (7.90+1.96) were signiicantly elevated in post treatment period when compared to pre treatment (7.58+1.96), (p= 0.023). Post treatment CRP, ESR and PC were signiicantly reduced when compared to pretreatment values (p=0.000, p=0.000 and p=0.025, respectively). In the pretreatment period, a direct correlation between ESR and PC values (r=0.036, p=0.025), and inverse correlations between ESR with MPV (r=-0.337, p=0.038) was found. A dependent predictive factor in multivariate logistic regression analysis for BSTAT was not found. Conclusion We suggest that PC and MPV may be inlammatory markers in brucellosis.en_US
dc.identifier.endpage39en_US
dc.identifier.issn1840-0132
dc.identifier.issue1en_US
dc.identifier.pmid23348158en_US
dc.identifier.scopus2-s2.0-84873851871en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage35en_US
dc.identifier.urihttp://acikerisim.ibu.edu.tr/xmlui/handle/20.500.12491/4920
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84873851871&partnerID=40&md5=895959c2d12a2da506faa7bddee826d4
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorHakyemez, İsmail Necati
dc.language.isoenen_US
dc.publisherMedical Association of Zenica-Doboj Cantonen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute-Phase Reactionen_US
dc.subjectBlood Plateletsen_US
dc.subjectInlammationen_US
dc.titleCould thrombocyte parameters be an inflammatory marker in the brucellosis?en_US
dc.typeArticleen_US

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