The relation between impaired glucose tolerance and slow coronary flow

Basit Öğe Kaydı
dc.authorid0000-0003-4976-6720en_US
dc.authorid0000-0003-2541-4675
dc.authorid0000-0002-6453-0073
dc.contributor.authorBinak, Emrah
dc.contributor.authorGündüz, Hüseyin
dc.contributor.authorŞahin, Müslüm
dc.contributor.authorKurtoğlu, Nuri
dc.contributor.authorDindar, İsmet
dc.date.accessioned2021-06-23T19:19:00Z
dc.date.available2021-06-23T19:19:00Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Impaired glucose tolerance is a preliminary stage in the development of type 2 diabetes mellitus and has been shown to increase the risk of cardiovascular morbidity and mortality in addition to causing endothelial dysfunction. In this study, we sought to determine if impaired glucose tolerance is related to slow coronary flow, an angiographic phenomenon caused by coronary micro and macrovascular endothelial dysfunction. Methods: The population of this prospective study consisted of 28 patients with documented slow coronary flow, defined according to TIMI frame count method, [20 (71.4%) males; 51 +/- 9 years] and 30 patients with normal coronary flow [17 (56.6%) males; 47 +/- 6 years]. All study patients underwent an oral glucose tolerance test after 12 h of fasting. Lipid profile, hemoglobin Ale and systemic blood pressure were measured in all patients. Results: There was no difference between two groups with respect to age, fasting plasma glucose, triglyceride, total cholesterol, high density lipoprotein, low density lipoprotein, hemoglobin Ale, systolic-diastolic blood pressure levels, history of smoking and alcohol consumption. Plasma glucose at 2 h of oral glucose tolerance test was significantly higher in slow coronary flow patients compared to control group (145 +/- 44 vs. 112 +/- 38 mg/dl, P=0.001, respectively). In addition, the number of patients who met the criteria of impaired glucose tolerance was significantly higher in slow coronary flow patient group [16 (57%) vs. 7 (23%), P=0.002, respectively). Conclusions: Our results suggest that impaired glucose tolerance may be an independent etiological factor for slow coronary flow phenomenon.en_US
dc.identifier.doi10.1016/j.ijcard.2005.09.007
dc.identifier.endpage146en_US
dc.identifier.issn0167-5273
dc.identifier.issue1en_US
dc.identifier.pmid16297474en_US
dc.identifier.scopus2-s2.0-33746316847en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage142en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijcard.2005.09.007
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5854
dc.identifier.volume111en_US
dc.identifier.wosWOS:000240044400023en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGündüz, Hüseyin
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSlow Coronary Flowen_US
dc.subjectImpaired Glucose Toleranceen_US
dc.subjectEndotheliumen_US
dc.titleThe relation between impaired glucose tolerance and slow coronary flowen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
emrah-binak.pdf
Boyut:
98.31 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/ Full text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu