Risk factors affecting seizure recurrence in childhood epilepsy during short?term follow?up

dc.authorid0000-0002-3613-0523en_US
dc.authorid0000-0003-3752-0846en_US
dc.authorid0000-0002-1795-5677en_US
dc.contributor.authorKılınç, Yasemin Baranoğlu
dc.contributor.authorHancı, Fatma
dc.contributor.authorAnkaralı, Handan
dc.contributor.authorAnkaralı, Seyit
dc.contributor.authorKabakuş, Nimet
dc.date.accessioned2023-06-01T11:42:46Z
dc.date.available2023-06-01T11:42:46Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose The aim of this study is to examine the factors affecting seizure recurrence in pediatric patients diagnosed with epilepsy. Methods Three hundred patients presenting to the pediatric neurology clinic between 2015 and 2018 and diagnosed with epilepsy and treated with single antiseizure drug were included in the study. Medical histories and clinical and laboratory findings were retrieved retrospectively from the hospital data system. The combined and adjusted effects of risk factors on seizure recurrence were evaluated using multivariate binary logistic regression analysis. Results Boys had a higher rate of seizure recurrence than girls. Seizure recurrence was also higher in patients with abnormal neurological examinations at the time of diagnosis compared to those with normal neurological examinations. Seizure recurrence was significantly higher in patients with global growth retardation. Epilepsy patients with abnormal MRI findings also had a higher rate of seizure recurrence than patients with normal neuroimaging findings. In addition, seizure recurrence was significantly higher in epilepsy patients with comorbidities such as cerebral palsy and autism spectrum disorders compared to patients without comorbidities. No significant association was observed between seizure recurrence and the first drug, perinatal asphyxia history, localization of epileptiform discharges on EEG, family history of epilepsy, family history of febrile seizures, history of stay in the neonatal intensive care unit during the perinatal period, or preterm delivery. Conclusion Abnormal neurological examination, abnormal neuroimaging and accompanying comorbidities, and global growth retardation at the time of diagnosis are important factors affecting seizure recurrence in pediatric patients with epilepsy.en_US
dc.identifier.citationKilinc, Y. B., Hancı, F., Ankaralı, H., Ankaralı, S., & Kabakus, N. (2021). Risk factors affecting seizure recurrence in childhood epilepsy during short-term follow-up. Child's Nervous System, 37(9), 2857-2863.en_US
dc.identifier.doi10.1007/s00381-021-05227-3
dc.identifier.endpage2863en_US
dc.identifier.issn0256-7040
dc.identifier.issn1433-0350
dc.identifier.issue9en_US
dc.identifier.pmid34050392en_US
dc.identifier.scopus2-s2.0-85106708989en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2857en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s00381-021-05227-3
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11047
dc.identifier.volume37en_US
dc.identifier.wosWOS:000655820400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKılınç, Yasemin Baranoğlu
dc.institutionauthorHancı, Fatma
dc.institutionauthorKabakuş, Nimet
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofChilds Nervous Systemen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpilepsyen_US
dc.subjectChildhooden_US
dc.subjectSeizure Recurrenceen_US
dc.subjectRisk Factorsen_US
dc.subjectUnprovoked Seizuresen_US
dc.subjectChildrenen_US
dc.titleRisk factors affecting seizure recurrence in childhood epilepsy during short?term follow?upen_US
dc.typeArticleen_US

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