Copeptin (C-terminal provasopressin): A promising marker of arrhythmogenesis in arrhythmia prone subjects?
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Dosyalar
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Neurohormones have drawn particular attention in the recent years possibly due to their potential diagnostic and prognostic values in a variety of clinical conditions including congestive heart failure (CHF), acute myocardial infarction (AMI), etc. Among neurohormones, arginine vasopressin (AVP) has been known to be secreted by hypothalamus in response to hypovolemia and increased plasma osmolality [1], and was also demonstrated to be a marker of the presence and severity of CHF [2]. However as described below, the potential association between AVP system and arrhythmogenesis may also confer some important therapeutic and prognostic implications in arrhthmia-prone patients. In the recent years, due to the instability and rapid clerance [1], the clinical utility of AVP has been gradually abandoned to some degree, and copeptin (CP), another novel neurohormone of the AVP system, has come into use in the clinical practice.
Açıklama
Anahtar Kelimeler
Copeptin, Arrhythmogenesis, Arrhythmia Prone Subjects
Kaynak
International Journal Of Cardiology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
148
Sayı
1