Is uric acid elevation a random finding or a causative agent of diabetic nephropathy?

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-4201-9757en_US
dc.authorid0000-0003-3085-7964en_US
dc.authorid0000-0002-3836-2125en_US
dc.authorid0000-0002-7422-1442
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorAktaş, Gülali
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorTel, Burçin Meryem Atak
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:50:54Z
dc.date.available2021-06-23T19:50:54Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: In this study, we aimed to analyze the relationship between serum uric acid (UA) and microalbuminuria as a marker of renal injury in type 2 diabetes mellitus. METHODS: A total of 100 patients with type 2 diabetes mellitus were enrolled in the study. Participants were divided into two groups according to the urinary microalbumin/creatinine ratio: diabetic nephropathy and non-nephropathy group. UA and microalbuminuria were compared between the study groups. RESULTS: Serum UA levels of diabetic nephropathy patients were significantly higher than those in the non-nephropathy group (UA in patients with diabetic nephropathy groups: 6.3 (1.82) mg/dl, UA in patients of the non-nephropathic group: 4.85(1.92) mg/dl)(p<0.001). There was a correlation between microalbuminuria and UA (r=0.238). This correlation was statistically significant (p=0.017). CONCLUSION: UA levels may be an important predictor of nephropathy in diabetic patients.en_US
dc.identifier.doi10.1590/1806-9282.65.9.1156
dc.identifier.endpage1160en_US
dc.identifier.issn1806-9282
dc.identifier.issue9en_US
dc.identifier.pmid31618330en_US
dc.identifier.scopus2-s2.0-85073425018en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1156en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.65.9.1156
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9886
dc.identifier.volume65en_US
dc.identifier.wosWOS:000489576700007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorAktaş, Gülali
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUric Aciden_US
dc.subjectDiabetic Nephropathiesen_US
dc.subjectAlbuminuriaen_US
dc.titleIs uric acid elevation a random finding or a causative agent of diabetic nephropathy?en_US
dc.typeArticleen_US

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