Effects of energy drinks on serum VEGF and bFGF levels during wound healing

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dc.authorid0000-0002-0073-3170en_US
dc.authorid0000-0002-5099-5128
dc.authorid0000-0003-3390-4623
dc.contributor.authorToptaş, Orçun
dc.contributor.authorTek, Mustafa
dc.contributor.authorAkkaş, İsmail
dc.contributor.authorKazancıoğlu, Hakkı Oğuz
dc.contributor.authorTosun, Mehmet
dc.contributor.authorÖzan, Fatih
dc.date.accessioned2021-06-23T19:42:37Z
dc.date.available2021-06-23T19:42:37Z
dc.date.issued2015
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Ağız Diş ve Çene Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractIntroduction: Energy drinks consist of many substances like caffeine, taurine, sucrose/glucose, vitamins and some herbal supplements like ginseng, gingko biloba and guarana and are used by millions of people world-wide. The study aims to investigate the effect of energy drinks on blood vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) levels. Material and method: Thirty male adult Wistar albino rats were randomly assigned to two groups, an experimental group (EG) and the control group (CG). The Red Bull (3.57 mL/kg/day equivalent to a person weighing 70 kg consuming 250 mL per day) was given by oral gavage to the EG and the same volume of water was given by oral gavage to CG. The full thickness 5 cm diameter skin incisions were performed on the back of the rats. The blood samples were taken from the rats (n=5 in each group) on the 3rd, 7th and 14th days of the experiment. The biochemical blood analysis was performed at the end of the experiment. Results: The 3rd day, mean VEGF values of EG and CO were statistically different. Similarly, on the 14th day, mean bFGF values of EG and CG were statistically different. On the 7th day, there were no statistically differences between mean VEGF and bFGF values of EG and CG. Discussion: The ingredients of energy drinks may affect the wound healing positively or negatively with many mechanisms described in literature. Our results confirmed that energy drinks may accelerate angiogenesis in early and late stages of the proliferation phase of wound healing. Further investigations may reveal more reliable results.en_US
dc.identifier.endpage159en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84944276103en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage155en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8554
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000346319200025
dc.identifier.volume31en_US
dc.identifier.wosWOS:000346319200025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorToptaş, Orçun
dc.institutionauthorTek, Mustafa
dc.institutionauthorAkkaş, İsmail
dc.institutionauthorTosun, Mehmet
dc.institutionauthorÖzan, Fatih
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEnergy Drinken_US
dc.subjectVEGFen_US
dc.subjectbFGFen_US
dc.subjectWound Healingen_US
dc.titleEffects of energy drinks on serum VEGF and bFGF levels during wound healingen_US
dc.typeArticleen_US

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